| Description : |
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
68 kDa |
| AA Sequence : |
MAGGPGPGEPAAPGAQHFLYEVPPW VMCRFYKVMDALEPADWCQFAALIV RDQTELRLCERSGQRTASVLWPWIN RNARVADLVHILTHLQLLRARDIIT AWHPPAPLPSPGTTAPRPSSIPAPA EAEAWSPRKLPSSASTFLSPAFPGS QTHSGPELGLVPSPASLWPPPPSPA PSSTKPGPESSVSLLQGARPSPFCW PLCEISRGTHNFSEELKIGEGGFGC VYRAVMRNTVYAVKRLKENADLEWT AVKQSFLTEVEQLSRFRHPNIVDFA GYCAQNGFYCLVYGFLPNGSLEDRL HCQTQACPPLSWPQRLDILLGTARA IQFLHQDSPSLIHGDIKSSNVLLDE RLTPKLGDFGLARFSRFAGSSPSQS SMVARTQTVRGTLAYLPEEYIKTGR LAVDTDTFSFGVVVLETLAGQRAVK THGARTKYLVYERLEKLQAVVAGVP GHLEAASCIPPSPQENSYVSSTGRA HSGAAPWQPLAAPSGASAQAAEQLQ RGPNQPVESDESLGGLSAALRSWHL TPSCPLDPAPLREAGCPQGDTAGES SWGSGPGSRPTAVEGLALGSSASSS SEPPQIIINPARQKMVQKLALYEDG ALDSLQLLSSSSLPGLGLEQDRQGP EESDEFQSTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
