Recombinant Human LGALS3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LGALS3-693H
• Product Overview: LGALS3 MS Standard C13 and N15-labeled recombinant protein (NP_002297) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.2 kDa
• AA Sequence: MADNFSLHDALSGSGNPNPQGWPGA WGNQPAGAGGYPGASYPGAYPGQAP PGAYPGQAPPGAYHGAPGAYPGAPA PGVYPGPPSGPGAYPSSGQPSAPGA YPATGPYGAPAGPLIVPYNLPLPGG VVPRMLITILGTVKPNANRIALDFQ RGNDVAFHFNPRFNENNRRVIVCNT KLDNNWGREERQSVFPFESGKPFKI QVLVEPDHFKVAVNDAHLLQYNHRV KKLNEISKLGISGDIDLTSASYTMI TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LGALS3 galectin 3 [ Homo sapiens (human) ]
• Official Symbol: LGALS3
• Synonyms: LGALS3; lectin, galactoside-binding, soluble, 3; LGALS2; galectin-3; galectin 3; GALIG; MAC 2; lectin L-29; 35 kDa lectin; MAC-2 antigen; IgE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35; L31; GAL3; MAC2; CBP35; GALBP
• Gene ID: 3958
• mRNA Refseq: NM_002306
• Protein Refseq: NP_002297
• MIM: 153619
• UniProt ID: P17931