Recombinant Human MAP4K2 Protein, MYC/DDK-tagged

Cat.No. : MAP4K2-387H
Product Overview : Recombinant human MAP4K2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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Description : The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 91.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : mitogen-activated protein kinase kinase kinase kinase 2 [ Homo sapiens ]
Official Symbol : MAP4K2
Synonyms : BL44; GCK; RAB8IP
Gene ID : 5871
mRNA Refseq : NM_004579.3
Protein Refseq : NP_004570.2
MIM : 603166
UniProt ID : Q12851

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