Recombinant Human MAP4K2 Protein, MYC/DDK-tagged

• Cat.No.: MAP4K2-387H
• Product Overview: Recombinant human MAP4K2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 91.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mitogen-activated protein kinase kinase kinase kinase 2 [ Homo sapiens ]
• Official Symbol: MAP4K2
• Synonyms: BL44; GCK; RAB8IP
• Gene ID: 5871
• mRNA Refseq: NM_004579.3
• Protein Refseq: NP_004570.2
• MIM: 603166
• UniProt ID: Q12851