Recombinant Human MAPK8 protein, His/MBP-tagged
| Cat.No. : | MAPK8-156H |
| Product Overview : | Recombinant Human MAPK8(1-72 aa) fused with His/MBP tag was expressed in E. coli. |
- Specification
- Gene Information
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| Description : | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His/MBP |
| Form : | Liquid in PBS |
| Protein length : | 1-72 aa |
| Purity : | SDS-PAGE >90% |
| Applications : | WB Positive Control |
| Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
| Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Gene Name : | MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ] |
| Official Symbol : | MAPK8 |
| Synonyms : | MAPK8; mitogen-activated protein kinase 8; PRKM8; JNK; JNK1; JUN N terminal kinase; SAPK1; MAP kinase 8; JUN N-terminal kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase 1c; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; |
| Gene ID : | 5599 |
| mRNA Refseq : | NM_002750 |
| Protein Refseq : | NP_002741 |
| MIM : | 601158 |
| UniProt ID : | P45983 |
Products Types
| ◆ Recombinant Protein | ||
| MAPK8-1136H | Recombinant Human MAPK8 Protein (S2-E364), Tag Free | +Inquiry |
| Mapk8-3945M | Recombinant Mouse Mapk8 Protein, Myc/DDK-tagged | +Inquiry |
| MAPK8-1137H | Recombinant Human MAPK8 Protein (S2-E364), His tagged | +Inquiry |
| MAPK8-3435H | Recombinant Human MAPK8 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAPK8-2420H | Recombinant Human MAPK8 Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| MAPK8-4489HCL | Recombinant Human MAPK8 293 Cell Lysate | +Inquiry |
| MAPK8-4488HCL | Recombinant Human MAPK8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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