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Recombinant Human MEN1 Protein, MYC/DDK-tagged

Cat.No.: MEN1-35H
Product Overview: Recombinant protein of human multiple endocrine neoplasia I (MEN1), transcript variant 2 with C-MYC/DDK tag was expressed in HEK293T.
Description: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
Source: HEK293
Species: Human
Tag : MYC/DDK
Molecular Mass: 67.3 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: MEN1
Official Symbol: MEN1 menin 1 [ Homo sapiens (human) ]
Synonyms: MEN1; menin 1; MEAI; SCG2
Gene ID: 4221
mRNA Refseq: NM_000244
Protein Refseq: NP_000235
MIM: 613733
UniProt ID: O00255

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