Recombinant Human MICA Protein, GST-tagged
Cat.No. : | MICA-5319H |
Product Overview : | Human MICA full-length ORF ( NP_000238.1, 1 a.a. - 383 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 69.3 kDa |
AA Sequence : | MGLGPVFLLLAGIFPFAPPGAAAEP HSLRYNLTVLSWDGSVQSGFLTEVH LDGQPFLRCDRQKCRAKPQGQWAED VLGNKTWDRETRDLTGNGKDLRMTL AHIKDQKEGLHSLQEIRVCEIHEDN STRSSQHFYYDGELFLSQNLETKEW TMPQSSRAQTLAMNVRNFLKEDAMK TKTHYHAMHADCLQELRRYLKSGVV LRRTVPPMVNVTRSEASEGNITVTC RASGFYPWNITLSWRQDGVSLSHDT QQWGDVLPDGNGTYQTWVATRICQG EEQRFTCYMEHSGNHSTHPVPSGKV LVLQSHWQTFHVSAVAAAAIFVIII FYVRCCKKKTSAAEGPELVSLQVLD QHPVGTSDHRDATQLGFQPLMSDLG STGSTEGA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MICA MHC class I polypeptide-related sequence A [ Homo sapiens ] |
Official Symbol : | MICA |
Synonyms : | MICA; MHC class I polypeptide-related sequence A; PERB11.1; HLA class I antigen; stress inducible class I homolog; MHC class I chain-related protein A; MIC-A; FLJ36918; FLJ60820; MGC21250; MGC111087; |
Gene ID : | 100507436 |
mRNA Refseq : | NM_000247 |
Protein Refseq : | NP_000238 |
MIM : | 600169 |
UniProt ID : | Q29983 |
Products Types
◆ Recombinant Protein | ||
MICA-1235H | Recombinant Human MICA Protein, MYC/DDK-tagged | +Inquiry |
MICA-823H | Recombinant Human MICA Protein | +Inquiry |
MICA-706H | Active Biotinylated Recombinant Human MICA Protein (Ala23-Gln308), Fc/Avi tagged | +Inquiry |
MICA-1232H | Recombinant Human MICA Protein, Fc-tagged | +Inquiry |
MICA-401C | Recombinant Cynomolgus MICA Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MICA-1941HCL | Recombinant Human MICA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionMICA expression can change during viral infections and influence the immune response to the pathogen.
Monoclonal antibodies and immunotherapies can target MICA on cancer cells, making them more susceptible to immune system attack.
Yes, tests like immunohistochemistry and flow cytometry can measure MICA expression on tumor cells and help in cancer diagnosis and treatment planning.
Altered MICA expression has been associated with some autoimmune diseases, such as rheumatoid arthritis, suggesting a potential role in disease development.
Yes, MICA polymorphisms can influence the success of organ transplantation by affecting the compatibility between donor and recipient.
Customer Reviews (3)
Write a reviewwhen utilized in Western Blotting experiments, the MICA protein has consistently produced distinct and well-defined protein bands, facilitating clear and accurate interpretation of results.
I have successfully implemented the MICA protein in protein electron microscopy structure analysis, where its attributes have greatly aided in elucidating complex molecular structures.
Considering its remarkable performance across multiple assays, I wholeheartedly endorse the usage of the MICA protein in various research studies.
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