Recombinant Human NTF3(139-257aa) NTF3-011H

Recombinant Human NTF3(139-257aa)


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Cat.No. : NTF3-011H Optional Service: Optional requirements on this protein
Product Overview : Human NTF3 (P20783, 139 a.a. - 257 a.a.) partial recombinant protein expressed in Escherichia coli.
Description : Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. NT-3 was the third neurotrophic factor to be characterized, after nerve growth factor (NGF) and BDNF.
Theoretical MW (kDa) : 14
Form : Lyophilized
Preparation Method : E. coli expression system
Purity : > 97% by SDS-PAGE and HPLC
Endotoxin Level : < 0.1 ng/ug (1 EU/ug)
Activity : The ED50 was determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 10-50 ng/mL.
Application : SDS-PAGE
Storage : Store at -20°C on dry atmosphere for 2 years.After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P20783
Pathways : Neurotrophin signaling pathway; MAPK signaling pathway
PDB rendering basedon 1b8k. :

Gene Name : NTF3 neurotrophin 3 [ Homo sapiens ]
Official Symbol : NTF3
Synonyms : NTF3; neurotrophin 3; NT3; HDNF; NGF2; NGF-2; MGC129711; neurotrophin-3; NT-3; OTTHUMP00000239132; OTTHUMP00000239133; neurotrophic factor; nerve growth factor 2; NGF-2; NGF2
Gene ID : 4908
mRNA Refseq : NM_001102654
Protein Refseq : NP_001096124
MIM : 162660
Chromosome Location : 12p13
Function : growth factor activity; nerve growth factor binding; neurotrophin receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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