Recombinant Human PAX7 protein, T7/His-tagged

• Cat.No.: PAX7-132H
• Product Overview: Recombinant human Pax7 cDNA (520aa, Isoform_1) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 0.2 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFAALPGTVPRMMRPAPGQNYPR TGFPLEVSTPLGQGRVNQLGGVFIN GRPLPNHIRHKIVEMAHHGIRPCVI SRQLRVSHGCVSKILCRYQETGSIR PGAIGGSKPRQVATPDVEKKIEEYK RENPGMFSWEIRDRLLKDGHCDRST VPSGLVSSISRVLRIKFGKKEEEDE ADKKEDDGEKKAKHSIDGILGDKGN RLDEGSDVESEPDLPLKRKQRRSRT TFTAEQLEELEKAFERTHYPDIYTR EELAQRTKLTEARVQVWFSNRRARW RKQAGANQLAAFNHLLPGGFPPTGM PTLPPYQLPDSTYPTTTISQDGGST VHRPQPLPPSTMHQGGLAAAAAAAD TSSAYGARHSFSSYSDSFMNPAAPS NHMNPVSNGLSPQVMSILGNPSAVP PQPQADFSISPLHGGLDSATSISAS CSQRADSIKPGDSLPTSQAYCPPTY STTGYSVDPVAGYQYGQYGQSECLV PWASPVPIPSPTPRASCLFMESYKV VSGWGMSISQMEKLKSSQMEQFT
• Purity: >90% by SDS-PAGE
• Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.
• Publication:
  DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD (2020)

Gene Information

• Gene Name: PAX7 paired box 7 [ Homo sapiens ]
• Official Symbol: PAX7
• Synonyms: PAX7; paired box 7; paired box gene 7; paired box protein Pax-7; Hup1; paired domain gene 7; paired box homeotic gene 7; PAX7 transcriptional factor; HUP1; RMS2; PAX7B; FLJ37460
• Gene ID: 5081
• mRNA Refseq: NM_001135254
• Protein Refseq: NP_001128726
• MIM: 167410
• UniProt ID: P23759
• Chromosome Location: 1p36.13
• Pathway: Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity