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Recombinant Human PDE5A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : PDE5A-2039H
Product Overview : PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Source : HEK293
Species : Human
Tag : Myc&DDK
Molecular Mass : 94.6 kDa
AA Sequence : MLPFGDKTREMVNAWFAERVHTIPV CKEGIRGHTESCSCPLQQSPRADNS APGTPTRKISASEFDRPLRPIVVKD SEGTVSFLSDSEKKEQMPLTPPRFD HDEGDQCSRLLELVKDISSHLDVTA LCHKIFLHIHGLISADRYSLFLVCE DSSNDKFLISRLFDVAEGSTLEEVS NNCIRLEWNKGIVGHVAALGEPLNI KDAYEDPRFNAEVDQITGYKTQSIL CMPIKNHREEVVGVAQAINKKSGNG GTFTEKDEKDFAAYLAFCGIVLHNA QLYETSLLENKRNQVLLDLASLIFE EQQSLEVILKKIAATIISFMQVQKC TIFIVDEDCSDSFSSVFHMECEELE KSSDTLTREHDANKINYMYAQYVKN TMEPLNIPDVSKDKRFPWTTENTGN VNQQCIRSLLCTPIKNGKKNKVIGV CQLVNKMEENTGKVKPFNRNDEQFL EAFVIFCGLGIQNTQMYEAVERAMA KQMVTLEVLSYHASAAEEETRELQS LAAAVVPSAQTLKITDFSFSDFELS DLETALCTIRMFTDLNLVQNFQMKH EVLCRWILSVKKNYRKNVAYHNWRH AFNTAQCMFAALKAGKIQNKLTDLE ILALLIAALSHDLDHRGVNNSYIQR SEHPLAQLYCHSIMEHHHFDQCLMI LNSPGNQILSGLSIEEYKTTLKIIK QAILATDLALYIKRRGEFFELIRKN QFNLEDPHQKELFLAMLMTACDLSA ITKPWPIQQRIAELVATEFFDQGDR ERKELNIEPTDLMNREKKNKIPSMQ VGFIDAICLQLYEALTHVSEDCFPL LDGCRKNRQKWQALAEQQEKMLING ESGQAKRNTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : PDE5A phosphodiesterase 5A [ Homo sapiens (human) ]
Official Symbol : PDE5A
Synonyms : PDE5A; phosphodiesterase 5A, cGMP-specific; cGMP-specific 3,5-cyclic phosphodiesterase; phosphodiesterase isozyme 5; cGMP-specific phosphodiesterase PDE5A2; cGMP-specific phosphodiesterase type 5A; cGMP-binding cGMP-specific 3,5-cyclic nucleotide phosphodiesterase; CN5A; PDE5; CGB-PDE;
Gene ID : 8654
mRNA Refseq : NM_033430
Protein Refseq : NP_236914
MIM : 603310
UniProt ID : O76074

Not For Human Consumption!

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