Recombinant Human RYR1 Protein, His&GST-tagged
Cat.No. : | RYR1-2037H |
Product Overview : | Recombinant Human RYR1 Protein (His97-Cys392) with N-His&GST tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. |
Source : | E. coli |
Species : | Human |
Tag : | N-His&GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 63.2 kDa Accurate Molecular Mass: 63 kDa |
Protein length : | His97-Cys392 |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | RYR1 ryanodine receptor 1 [ Homo sapiens (human) ] |
Official Symbol : | RYR1 |
Synonyms : | Ryr1; ryanodine receptor 1; RYR-1; Ryr1l; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; skeletal muscle calcium release channel; skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; type 1 ryanodine receptor |
Gene ID : | 6261 |
mRNA Refseq : | NM_000540 |
Protein Refseq : | NP_000531 |
MIM : | 180901 |
UniProt ID : | P21817 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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