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Recombinant Human RYR1 protein (Skeletal), His-tagged

Cat.No. : RYR1-790H
Product Overview : Recombinant Human RYR1 protein (Skeletal, His97-Cys392), fused to His-tag at the N-terminus, was expressed in E.coli.
  • Specification
  • Gene Information
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Description : This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Source : E.coli
Species : Human
Tag : His
Form : Freeze-dried powder. 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Molecular Mass : Predicted Molecular Mass: 63.2 kDa; Accurate Molecular Mass: 63 kDa
Protein length : His97-Cys392
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : RYR1
Official Symbol : RYR1
Synonyms : CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; PPP1R137
Gene ID : 6261
mRNA Refseq : NM_000540.3
Protein Refseq : NP_000531.2
MIM : 180901
UniProt ID : P21817

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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