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Recombinant Human TDGF1 Protein, His-tagged(C-ter)

Cat.No. : TDGF1-295H
Product Overview : Recombinant Human TDGF1 Protein with His tag (C-ter) was expressed in HEK293.
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Description : This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Source : HEK293
Species : Human
Tag : His(C-ter)
Form : Powder
Protein Length : Leu31-Thr172
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 95% (by SDS-PAGE)
Applications : Binding, SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 7.4)
Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.
Gene Name : TDGF1 teratocarcinoma-derived growth factor 1 [ Homo sapiens ]
Official Symbol : TDGF1
Synonyms : TDGF1; teratocarcinoma-derived growth factor 1; CR; CRIPTO; Cripto 1; cripto-1 growth factor; epidermal growth factor-like cripto protein CR1; CRGF;
Gene ID : 6997
mRNA Refseq : NM_001174136
Protein Refseq : NP_001167607
UniProt ID : P13385

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is TDGF1 associated with any genetic disorders? 01/26/2021

Mutations in the TDGF1 gene have been linked to certain congenital disorders. Understanding these genetic associations can provide insights into the underlying mechanisms of these conditions.

How does TDGF1 influence neurodevelopment? 02/11/2020

TDGF1 has been found to play a role in neural development. It is involved in the specification of neural cell fate and the formation of the neural tube during embryogenesis.

Can TDGF1 be a target for drug development? 06/27/2019

Yes, efforts are underway to develop drugs that modulate TDGF1 activity. Targeting TDGF1 could potentially lead to novel therapies for conditions related to cell growth and differentiation.

In what ways does TDGF1 contribute to stem cell biology? 06/04/2019

TDGF1 is involved in the maintenance of pluripotency in embryonic stem cells. Understanding its role could enhance our ability to control and manipulate stem cells for therapeutic purposes.

How can TDGF1 be utilized in cancer diagnostics? 10/09/2016

Researchers are exploring the use of TDGF1 as a biomarker for certain cancers. Detection of elevated TDGF1 levels in patient samples may aid in early cancer diagnosis.

Customer Reviews (3)

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01/13/2020

    the manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of TDGF1 protein in trials.

    03/26/2018

      manufacturers often have a wealth of knowledge and expertise in the field of TDGF1 protein research.

      08/29/2017

        They may offer educational resources such as technical guides, protocols, and application notes, which can aid researchers in understanding the principles, techniques, and potential applications of TDGF1 protein in their studies.

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