Recombinant Mouse Adam8 protein, His-tagged
Cat.No. : | Adam8-616M |
Product Overview : | Recombinant Mouse Adam8 aa. (Glu145~Cys493) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 44kDa as determined by SDS-PAGE reducing conditions |
Protein length : | Glu145~Cys493 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.3. |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300 |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
Gene Name : | Adam8 a disintegrin and metallopeptidase domain 8 [ Mus musculus (house mouse) ] |
Official Symbol : | Adam8 |
Synonyms : | Adam8; a disintegrin and metallopeptidase domain 8; MS2; CD156; ADAM 8; CD156a; E430039A18Rik; disintegrin and metalloproteinase domain-containing protein 8; a disintegrin and metalloprotease domain 8; cell surface antigen MS2; macrophage cysteine-rich glycoprotein |
Gene ID : | 11501 |
mRNA Refseq : | NM_001291066.2 |
Protein Refseq : | NP_001277995.1 |
UniProt ID : | Q3U7G2 |
Products Types
◆ Recombinant Protein | ||
ADAM8-320M | Recombinant Mouse ADAM8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM8-086H | Recombinant Human ADAM8 Protein, His-tagged | +Inquiry |
ADAM8-2421H | Recombinant Human ADAM8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM8-004H | Recombinant Human ADAM8 Protein, C-His-tagged | +Inquiry |
ADAM8-615H | Recombinant Human ADAM8 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
ADAM8-855CCL | Recombinant Cynomolgus ADAM8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (14)
Ask a questionADAM8 is involved in various complex biological processes such as inflammation and osteoclastogenesis.
You can choose the product whose Cat.No. is ADAM8-086H.
ADAM8 cleaves important cell surface proteins, such as cytokines and growth factors.
We provide a variety of ADAM8 proteins, all of which are in stock except those that require custom production.
His has a smaller molecular weight and has less impact on protein activity.
No, ADAM8 can only be activated by removing the leading domain.
Propofol inhibits ADAM8 expression in pancreatic cancer cells.
Yes, you can first communicate with our experts about specific customization requirements.
The expression level of ADAM8 is usually low in normal tissues and is significantly increased in response to pathological stimuli.
Lead times for custom-manufactured recombinant proteins range from 5-9 weeks.
Yes, transcription factor SP1 binds to the promoter of ADAM8.
ADAM8 has two subtypes, the membrane type (ADAM8m) and the secretory type (ADAM8s).
ADAM8 is mainly used in the studies of breast, prostate and pancreatic cancers.
Yes, we will ship according to your specification after your purchase.
Customer Reviews (5)
Write a reviewThe ADAM8 protein received was of stable composition and high concentration, giving me satisfactory experimental results.
It is suitable for ELISA, and the help of technicians also made my experiments go smoothly.
The technician gave me a detailed introduction to the ADAM38 protein for the smooth running of the subsequent experiments.
The after-sales service of the product is guaranteed, which has helped me solve many problems in the experiment.
Good protein quality, good service attitude and affordable price.
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