Recombinant Mouse ADSSL1 Protein

• Cat.No.: ADSSL1-1392M
• Product Overview: Recombinant Mouse ADSSL1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Adssl1 adenylosuccinate synthetase like 1 [ Mus musculus ]
• Official Symbol: ADSSL1
• Gene ID: 11565
• mRNA Refseq: NM_007421.2
• Protein Refseq: NP_031447.1
• UniProt ID: P28650

Reviews

11/01/2020

Exploring protein-protein interactions involved in intracellular trafficking.

06/04/2019

Detecting protein-protein interactions in membrane receptor signaling.

01/05/2018

Understanding protein-protein interaction networks in DNA repair processes.

Q&As

How is the subcellular localization of ADSSL1 protein controlled, and are there any specific mechanisms or signals involved?

The subcellular localization of ADSSL1 protein is primarily within mitochondria, facilitated by mitochondrial targeting sequences and import machinery.

Are there any known post-translational modifications or regulatory factors that modulate the activity or stability of ADSSL1 protein?

Post-translational modifications, such as phosphorylation or acetylation, and regulatory factors like metabolic signals or protein-protein interactions, may modulate the activity or stability of ADSSL1 protein.

Does ADSSL1 protein interact with other proteins or participate in protein complexes, and if so, what are the functional implications?

ADSSL1 protein can interact with other enzymes involved in purine metabolism, forming complexes that regulate nucleotide synthesis and energy metabolism.

Are there any genetic variations or mutations in the ADSSL1 gene that impact the expression or function of ADSSL1 protein?

Genetic variations or mutations in the ADSSL1 gene can impact the expression or function of ADSSL1 protein, potentially leading to disorders associated with purine metabolism abnormalities.

What is the role of ADSSL1 protein in specific metabolic pathways or cellular processes?

ADSSL1 protein plays a critical role in purine nucleotide metabolism, contributing to the deamination and recycling of adenylosuccinate to maintain nucleotide homeostasis.

Are there any specific structural features or domains of ADSSL1 protein that contribute to its enzymatic activity and substrate specificity?

ADSSL1 protein contains conserved structural domains, including a catalytic domain and nucleotide-binding motifs, that contribute to its enzymatic activity and substrate specificity.

What is the enzymatic activity of ADSSL1 protein, and how is it measured in experimental assays?

The enzymatic activity of ADSSL1 protein, catalyzing the conversion of adenylosuccinate to AMP, can be measured using enzymatic assays that quantify substrate utilization and product formation.

What experimental approaches, such as knockout or overexpression studies, have been employed to investigate the functional significance of ADSSL1 protein?

Experimental approaches such as knockout or overexpression studies have been utilized to investigate the functional significance of ADSSL1 protein, revealing its role in cellular metabolism and energy balance.

What are the tissue-specific expression patterns of ADSSL1 protein and the factors that contribute to its regulation?

ADSSL1 protein exhibits tissue-specific expression, with higher levels observed in skeletal muscle, heart, and brain. Factors involved in its regulation include transcriptional control and signaling pathways.

How does dysregulation or dysfunction of ADSSL1 protein affect cellular metabolism and contribute to disease development?

Dysregulation or dysfunction of ADSSL1 protein can disrupt cellular purine metabolism, leading to imbalances in nucleotide levels and potential contributions to diseases such as neurodegenerative disorders or metabolic syndromes.