Recombinant Mouse Bccip Protein, Myc/DDK-tagged

• Cat.No.: Bccip-1845M
• Product Overview: Purified recombinant protein of mouse full-length BRCA2 and CDKN1A interacting protein (Bccip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 36.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bccip BRCA2 and CDKN1A interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Bccip
• Synonyms: BCCIP; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; TOK-1; 1110013J05Rik
• Gene ID: 66165
• mRNA Refseq: NM_025392
• Protein Refseq: NP_079668
• UniProt ID: Q9CWI3