Recombinant Mouse Cd6, His tagged

• Cat.No.: Cd6-6896M
• Product Overview: Recombinant Mouse Cd6 (Q91WN5) extracellular domain (Met 1-Val 243), fused with a C-terminal polyhistidine tag, was produced in Human Cell.

Specification

• Source: Human Cells
• Species: Mouse
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4
• Molecular Mass: The secreted recombinant mouse CD6 comprises 391 amino acids and has a calculated molecular mass of 42.6 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 70-80 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Protein length: Met1-Val243

Gene Information

• Gene Name: Cd6 CD6 antigen [ Mus musculus ]
• Official Symbol: Cd6
• Gene ID: 12511
• mRNA Refseq: NM_001037801
• Protein Refseq: NP_001032890

Reviews

04/05/2021

Fantastic customer support. They genuinely care about the success of our research.

11/11/2020

Quality you can trust. Our lab has seen improved precision since using this product.

07/27/2019

Shipping is always on time, and the packaging ensures the product arrives in perfect condition.

Q&As

Can you explain the role of CD6 in T-cell co-stimulation and its implications for adaptive immune responses?

CD6 provides co-stimulatory signals to T cells, influencing their activation and differentiation. This contributes to the regulation of adaptive immune responses.

How are CD6 genes polymorphic, and what is the significance of genetic variations in the context of autoimmune diseases?

CD6 genes exhibit polymorphisms, and certain variations are associated with susceptibility to autoimmune diseases, indicating a potential role in immune dysregulation.

How does CD6 contribute to the formation of immunological synapses, and what molecular events are involved in this process?

CD6 is involved in immunological synapse formation, and its interactions with ligands, such as ALCAM, play a role in stabilizing T-cell interactions with antigen-presenting cells.

How does CD6 influence T-cell trafficking and migration, and what are the implications for immune surveillance and inflammation?

CD6 modulates T-cell trafficking and migration, impacting immune surveillance and inflammation. Its interactions with adhesion molecules contribute to these processes.

What is the relationship between CD6 and antigen-presenting cells, and how does it impact the initiation of immune responses?

CD6 interacts with antigen-presenting cells, facilitating T-cell activation. This interaction is pivotal for the initiation and regulation of immune responses.