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Recombinant Mouse Cfh protein, hFc-tagged

Cat.No. : Cfh-396M
Product Overview : Recombinant Mouse Cfh protein(NP_034018.2)(Ser875-Val1252), fused with hFc tag, was expressed in HEK293.
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  • Gene Information
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Source : HEK293
Species : Mouse
Tag : hFc
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The recombinant mouse Cfh consists 616 amino acids and predicts a molecular mass of 69.1 kDa.
Protein Length : Ser875-Val1252
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 80 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Cfh complement component factor h [ Mus musculus ]
Official Symbol : Cfh
Synonyms : CFH; complement component factor h; complement factor H; protein beta-1-H; complement factor H related protein 3A4/5G4; NOM; Sas1; Mud-1; Sas-1;
Gene ID : 12628
mRNA Refseq : NM_009888
Protein Refseq : NP_034018

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the impact of CFH mutations on the risk of developing atypical hemolytic uremic syndrome (aHUS)? 02/13/2022

Mutations in CFH increase the risk of aHUS, affecting complement regulation and leading to kidney damage.

How does CFH (Complement Factor H) regulate the complement system and prevent overactivation? 06/07/2021

CFH controls the complement system, preventing its overactivation and protecting against immune damage.

How does CFH influence the immune response to bacterial infections? 01/07/2020

CFH modulates the immune response to bacterial infections, balancing defense mechanisms.

How does CFH deficiency contribute to the development of age-related macular degeneration (AMD)? 09/09/2019

CFH deficiency is linked to AMD, due to impaired regulation of the complement pathway in the retina.

What role does CFH play in protecting host cells from complement-mediated damage? 04/03/2019

CFH shields host cells from complement-mediated injury, maintaining tissue integrity.

What are the mechanisms by which CFH modulates inflammation and immune homeostasis? 01/23/2019

CFH regulates inflammation and maintains immune balance, crucial for preventing excessive immune responses.

How do alterations in CFH expression or function affect renal function and the development of kidney diseases? 01/18/2018

Changes in CFH function can impact kidney health, potentially leading to renal diseases due to altered complement activity.

Customer Reviews (3)

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Reviews
11/16/2020

    Exceptional protein expression optimization support, highly appreciated assistance.

    07/31/2020

      Precise protein quantification, ensures data accuracy in our research.

      03/10/2018

        Timely antibody validation, an invaluable asset for our laboratory.

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