Recombinant Mouse Ctsb Protein, His-tagged
Cat.No. : | Ctsb-28M |
Product Overview : | Recombinant mouse CTSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | CTSB, also known as cathepsin B preproprotein, is a papain-family cysteine protease that is normally located in lysosomes. It has the ability to degrade several extracellular matrix components at both neutral and acidic pH and has been implicated in the progression of several human and rodent tumors progression and arthritis. |
Source : | Insect cells |
Species : | Mouse |
Tag : | His tag |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 36.4kDa (330aa)28-40kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | HDKPSFHPLS DDLINYINKQ NTTWQAGRNF YNVDISYLKK LCGTVLGGPK LPGRVAFGED IDLPETFDAR EQWSNCPTIG QIRDQGSCGSCWAFGAVEAI SDRTCIHTNG RVNVEVSAED LLTCCGIQCG DGCNGGYPSG AWSFWTKKGL VSGGVYNSHV GCLPYTIPPC EHHVNGSRPPCTGEGDTPRC NKSCEAGYSP SYKEDKHFGY TSYSVSNSVK EIMAEIYKNG PVEGAFTVFS DFLTYKSGVY KHEAGDMMGG HAIRILGWGV ENGVPYWLAA NSWNLDWGDN GFFKILRGEN HCGIESEIVA GIPRTDQYWG RFLEHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | Ctsb cathepsin B [ Mus musculus ] |
Official Symbol : | Ctsb |
Synonyms : | CTSB; cathepsin B; cathepsin B1; CB; |
Gene ID : | 13030 |
mRNA Refseq : | NM_007798 |
Protein Refseq : | NP_031824 |
MIM : | |
UniProt ID : | |
Pathway : | Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; thyroid hormone biosynthesis, conserved biosystem; |
Function : | cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; hydrolase activity; kininogen binding; peptidase activity; peptide binding; protein complex binding; protein self-association; |
Products Types
◆ Recombinant Protein | ||
Ctsb-10530M | Recombinant Mouse Ctsb Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctsb-2367M | Recombinant Mouse Ctsb Protein, Myc/DDK-tagged | +Inquiry |
CTSB-3369H | Recombinant Human CTSB Protein, MYC/DDK-tagged | +Inquiry |
CTSB-2750H | Recombinant Human CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-175C | Recombinant Cynomolgus Monkey CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSB-188B | Active Native Bovine Cathepsin B | +Inquiry |
CTSB-5328H | Native Human Cathepsin B | +Inquiry |
CTSB-26408TH | Native Human CTSB | +Inquiry |
◆ Lysates | ||
CTSB-1885MCL | Recombinant Mouse CTSB cell lysate | +Inquiry |
CTSB-3025HCL | Recombinant Human CTSB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2366 | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCTSB affects extracellular matrix remodeling, relevant in joint diseases like osteoarthritis.
CTSB is implicated in neurodegenerative diseases, potentially contributing to protein aggregation and neuronal damage.
Variations in CTSB expression impact tissue repair processes and the development of fibrosis in various organs.
CTSB regulates apoptosis and cell survival, influencing cell fate decisions under stress or damage.
CTSB can influence cancer progression by modulating the tumor microenvironment and facilitating tumor cell invasion.
CTSB is involved in lysosomal protein degradation, essential for cellular waste disposal and recycling.
CTSB plays a role in inflammation, impacting immune cell function and inflammatory responses.
Customer Reviews (3)
Write a reviewExceptional protein engineering services, our trusted research partner.
Reliable protein crystallography, key for our structural biology research.
Swift protein quantification, improves data reliability in our work.
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