Recombinant Mouse Ctsb Protein, Myc/DDK-tagged
Cat.No. : | Ctsb-2367M |
Product Overview : | Purified recombinant protein of mouse full-length cathepsin B (Ctsb), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 37.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ctsb cathepsin B [ Mus musculus (house mouse) ] |
Official Symbol : | Ctsb |
Synonyms : | CTSB; cathepsin B; cathepsin B1; CB |
Gene ID : | 13030 |
mRNA Refseq : | NM_007798 |
Protein Refseq : | NP_031824 |
UniProt ID : | P10605 |
Products Types
◆ Recombinant Protein | ||
CTSB-2099H | Recombinant Human CTSB Protein, GST-tagged | +Inquiry |
CTSB-2750H | Recombinant Human CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-3369H | Recombinant Human CTSB Protein, MYC/DDK-tagged | +Inquiry |
Ctsb-10530M | Recombinant Mouse Ctsb Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-175C | Recombinant Cynomolgus Monkey CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSB-26408TH | Native Human CTSB | +Inquiry |
CTSB-5328H | Native Human Cathepsin B | +Inquiry |
CTSB-188B | Active Native Bovine Cathepsin B | +Inquiry |
◆ Lysates | ||
CTSB-3025HCL | Recombinant Human CTSB cell lysate | +Inquiry |
CTSB-1885MCL | Recombinant Mouse CTSB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2366 | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCTSB affects extracellular matrix remodeling, relevant in joint diseases like osteoarthritis.
CTSB is implicated in neurodegenerative diseases, potentially contributing to protein aggregation and neuronal damage.
Variations in CTSB expression impact tissue repair processes and the development of fibrosis in various organs.
CTSB regulates apoptosis and cell survival, influencing cell fate decisions under stress or damage.
CTSB can influence cancer progression by modulating the tumor microenvironment and facilitating tumor cell invasion.
CTSB is involved in lysosomal protein degradation, essential for cellular waste disposal and recycling.
CTSB plays a role in inflammation, impacting immune cell function and inflammatory responses.
Customer Reviews (3)
Write a reviewExceptional protein engineering services, our trusted research partner.
Reliable protein crystallography, key for our structural biology research.
Swift protein quantification, improves data reliability in our work.
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