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Recombinant Mouse Dcn Protein, Myc/DDK-tagged

Cat.No. : Dcn-2475M
Product Overview : Purified recombinant protein of mouse full-length decorin (Dcn), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 40.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Dcn decorin [ Mus musculus (house mouse) ]
Official Symbol : Dcn
Synonyms : DCN; decorin; bone proteoglycan II; DC; PG40; PGII; PGS2; mDcn; DSPG2; SLRR1B
Gene ID : 13179
mRNA Refseq : NM_001190451
Protein Refseq : NP_001177380
UniProt ID : P28654

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the effect of targeted DCN delivery on tumor growth in a mouse model of breast cancer? 07/10/2022

Targeted DCN delivery in breast cancer models reduces tumor growth.

How does DCN modulate TGF-β signaling at the molecular level? 05/06/2022

DCN modulates TGF-β signaling, affecting fibrosis and cancer development.

How do variations in the glycosaminoglycan chains attached to DCN influence its interaction with growth factors? 12/11/2021

Variations in DCN's glycosaminoglycan chains influence its growth factor interactions.

What are the cellular and molecular consequences of DCN gene silencing in fibroblasts? 12/07/2021

DCN gene silencing in fibroblasts alters extracellular matrix production and cell mobility.

How do mechanical forces influence the function and localization of DCN in the cardiac extracellular matrix? 04/30/2021

Mechanical forces impact DCN's role in cardiac matrix organization and cell signaling.

Which proteins are differentially expressed in cells overexpressing DCN compared to control cells? 10/14/2019

Overexpression of DCN changes protein expression related to cell growth and matrix interactions.

What is the detailed three-dimensional structure of DCN when bound to collagen? 07/27/2018

DCN bound to collagen reveals binding sites essential for collagen structure.

Customer Reviews (3)

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Reviews
03/11/2020

    Excellent support for protein purification. Highly recommend this service.

    11/01/2019

      Efficient protein expression, quick turnaround time, and reliable results.

      10/14/2019

        Outstanding antibody validation; trustworthy for protein-protein interaction studies.

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