Recombinant Mouse Git1 Protein, Myc/DDK-tagged

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Recombinant Mouse Git1 Protein, Myc/DDK-tagged

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Cat.No. : Git1-3215M
Product Overview : Purified recombinant protein of mouse full-length GIT ArfGAP 1 (Git1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve ENTR1 and PTPN13.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 85.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Git1 GIT ArfGAP 1 [ Mus musculus (house mouse) ]
Official Symbol : Git1
Synonyms : GIT1; G protein-coupled receptor kinase-interactor 1; ARF GTPase-activating protein GIT1; ARF GAP GIT1; GRK-interacting protein 1; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein; Cat-1; p95Cat
Gene ID : 216963
mRNA Refseq : NM_001004144
Protein Refseq : NP_001004144
UniProt ID : Q68FF6

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