Recombinant Mouse Il23a & Il12b, His tagged

Cat.No. : IL23A-159M
Product Overview : Recombinant Mouse Il23a & Il12b (Q9EQ14 & P43432) (Met1-Ala196 & Met1-Ser335), fused with A DNA sequence encoding the mouse IL23A (Q9EQ14) (Met1-Ala196 ) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encod
  • Specification
  • Gene Information
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Source : Human Cells
Species : Mouse
Tag : His
Predicted N Terminal : Val 22 & Met 23
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant mouse IL23 (mouse IL23A&IL12B Heterodimer) comprises 510 (186+324) amino acids and has a calculated molecular mass of 58.3 (21.1+ 37.2) KDa. The apparent molecular mass of the recombinant protein is approximately 47,45 and 26 KDa respectiv
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : (33.1+31.5+32.9) % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4oC before opening to recover the entire contents.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is this bioactive cyno IL-23 heterodimer (p19/p40) or just the cyno IL-23p19 subunit? 02/01/2023

Please inquiry our product manager with specific product.

Are there any FDA-approved drugs targeting IL23A? 12/22/2021

Yes, drugs like ustekinumab and risankizumab, which target IL23A, have been approved for certain autoimmune diseases.

Is IL23A involved in the regulation of adaptive or innate immunity? 08/23/2018

IL23A primarily plays a role in regulating the adaptive immune response.

How is IL23A linked to the pathogenesis of ankylosing spondylitis? 01/25/2018

IL23A is associated with the inflammation of the spine and joints seen in ankylosing spondylitis, making it a target for therapeutic intervention.

How does IL23A contribute to rheumatoid arthritis? 09/01/2017

In rheumatoid arthritis, IL23A is involved in the dysregulation of the immune system, leading to joint inflammation and damage.

How is IL23A involved in inflammatory bowel diseases like Crohn's disease? 07/03/2016

IL23A is implicated in the pathogenesis of Crohn's disease, contributing to chronic inflammation in the gastrointestinal tract.

Customer Reviews (3)

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Reviews
04/18/2020

    Coupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the IL23A protein in their studies, knowing that they have the necessary resources and assistance to succeed.

    12/02/2016

      Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.

      02/25/2016

        Highly recommended for its exceptional performance in ELISA, the IL23A protein is a top contender for researchers involved in protein electron microscopy structure analysis.

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