Recombinant Mouse Il9r protein, His-tagged
|Product Overview :||Recombinant Mouse Il9r protein(NP_001127930.1)(Gly47~Gln257) fused to His-tag at N-terminus, was expressed in E. coli.|
- Gene Information
- Related Products
|Source :||E. coli|
|Form :||20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.|
|Molecular Mass :||29kDa as determined by SDS-PAGE reducing conditions.|
|Protein length :||Gly47~Gln257|
|AA Sequence :||GQKAGAFTCLSNSIYRIDCHWSAPE LGQESRAWLLFTSNQVTEIKHKCTF WDSMCTLVLPKEEVFLPFDNFTITL HRCIMGQEQVSLVDSQYLPRRHIKL DPPSDLQSNVSSGRCVLTWGINLAL EPLITSLSYELAFKRQEEAWEARHK DRIVGVTWLILEAVELNPGSIYEAR LRVQMTLESYEDKTEGEYYKSHWSE WSQPVSFPSPQ|
|Endotoxin :||<1.0EU per 1µg (determined by the LAL method).|
|Purity :||>95% as determined by SDS-PAGE.|
|Applications :||Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
|Notes :||The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.|
|Reconstitution :||Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.|
|Gene Name :||Il9r|
|Official Symbol :||Il9r|
|Synonyms :||CD129; IL9-R; Cluster Of Differentiation 129|
|Gene ID :||16199|
|mRNA Refseq :||NM_001134458.1|
|Protein Refseq :||NP_001127930.1|
|UniProt ID :||Q01114|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
In pre-clinical trials, the IL9R significantly increased natural killer and CD4 + T cell levels in patients.
IL9R may play an important role in the treatment of central nervous system diseases and hematological diseases.
This needs to be further confirmed by large-scale clinical trials.
This can be achieved through in vitro molecular cell techniques and carefully designed in vivo animal models.
There have been no large-scale clinical studies to prove which diseases the recombinant IL9R protein can treat.
Some studies have suggested that the expression of IL9R in tumor cells may be associated with patient prognosis.
Customer Reviews (3)Write a review
IL-9R belongs to the cell membrane receptor family, which includes multiple subunits. Different types of IL-9R may have different structures and involve different signal transduction mechanisms, and these structural properties need to be fully considered during the production process. -
Purification of IL-9R is relatively complex due to its transmembrane structure and complexity. Common purification methods include affinity chromatography, centrifugation, gel filtration and other technologies to obtain high purity IL-9R. -
The biological activity of IL-9R is verified by using methods such as cell culture, cell chemotactic assay, or enzym-linked immunosorbent assay, which can evaluate the binding capacity and signaling effect of IL-9R with its ligand, such as IL-9. -
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