Recombinant Mouse INPP5B Protein

• Cat.No.: INPP5B-8226M
• Product Overview: Recombinant Mouse INPP5B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Inpp5b inositol polyphosphate-5-phosphatase B [ Mus musculus ]
• Official Symbol: INPP5B
• Gene ID: 16330
• mRNA Refseq: NM_008385.3
• Protein Refseq: NP_032411.3
• UniProt ID: Q8K337

Reviews

02/15/2020

We found the product's straightforward protocols highly conducive to seamless integration into our lab work.

10/17/2017

Clear and concise instructions simplified the application of the product, reducing the learning curve.

06/18/2017

We appreciated the product's efficiency in achieving target protein upregulation with minimal time investment.

Q&As

What is the subcellular localization of INPP5B?

INPP5B is primarily located in the cytoplasm, where it functions to regulate inositol phosphate levels within the cell.

How is INPP5B activity regulated?

The activity of INPP5B can be regulated through post-translational modifications and interactions with other proteins.

What is the role of INPP5B in cellular signaling?

INPP5B regulates cellular signaling by controlling the levels of inositol phosphates, which are essential secondary messengers in various cellular pathways.

Is there any research on INPP5B as a therapeutic target?

INPP5B is a subject of research in cancer therapy, as its modulation may affect the behavior of cancer cells.

What is INPP5B?

INPP5B is an enzyme involved in the dephosphorylation of inositol phosphates, specifically in the conversion of inositol 1,4,5-trisphosphate (IP3) to inositol 1,4-bisphosphate.

In which cellular processes does INPP5B play a role?

INPP5B is involved in regulating processes such as cell growth, proliferation, and cytoskeletal dynamics through its influence on inositol phosphate signaling.

What are the implications of INPP5B dysregulation?

Dysregulation of INPP5B can impact various cellular functions and has been associated with conditions like cancer, as it can alter signaling pathways that control cell growth and survival.