Recombinant Mouse MERTK protein, Fc-tagged
Cat.No. : | MERTK-2194M |
Product Overview : | Recombinant Mouse MERTK protein(NP_032613.1)(Gly 19 - Met 497), fused with Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | Fc |
Form : | PBS, pH7.4 |
Molecular Mass : | 78.9 kDa |
Protein length : | Gly 19 - Met 497 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by reduced SDS-PAGE. |
Storage : | This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended to reconstitute the lyophilized powder in sterile water to 100-200 ug/ml, and further dilute with other solvents. The dissolved protein can be stored at 4°C for 2-7 days and should be used up as soon as possible. If not in use for a short time, please store at -20°C. |
Gene Name : | Mertk c-mer proto-oncogene tyrosine kinase [ Mus musculus ] |
Official Symbol : | MERTK |
Synonyms : | MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; Tyro 12; proto-oncogene c-Mer; receptor tyrosine kinase MerTK; proto-oncogene tyrosine-protein kinase Mer; Eyk; Mer; Nyk; nmf12; |
Gene ID : | 17289 |
mRNA Refseq : | NM_008587 |
Protein Refseq : | NP_032613 |
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◆ Lysates | ||
MERTK-2888HCL | Recombinant Human MERTK cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewFast shipping and excellent service. This product is a lab essential.
Highly recommend for quality and prompt delivery.
Exceptional product, outstanding customer service!
Q&As (5)
Ask a questionMERTK's involvement in cancer includes promoting tumor cell survival and metastasis. Targeting MERTK is under investigation as a potential therapeutic strategy in cancer treatment.
The Gas6-MERTK signaling axis influences diverse cellular processes, activating downstream effectors such as PI3K/Akt and MAPK pathways. Understanding these signaling events provides insights into MERTK's functional diversity.
MERTK is involved in microglial phagocytosis and synaptic pruning, contributing to neural circuitry development. Dysregulation may affect synaptic connectivity, with implications for neurodevelopmental disorders.
MERTK is involved in immune regulation, influencing inflammatory responses. Dysregulation of MERTK has been implicated in autoimmune disorders, emphasizing its role in maintaining immune homeostasis.
Techniques such as co-immunoprecipitation, flow cytometry, and advanced imaging methods are commonly used to study MERTK, providing insights into ligand interactions, signaling pathways, and cellular functions.
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