Recombinant Mouse Mgmt Protein, Myc/DDK-tagged

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Recombinant Mouse Mgmt Protein, Myc/DDK-tagged

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Cat.No. : Mgmt-4062M
Product Overview : Purified recombinant protein of mouse full-length O-6-methylguanine-DNA methyltransferase (Mgmt), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 22.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Mgmt O-6-methylguanine-DNA methyltransferase [ Mus musculus (house mouse) ]
Official Symbol : Mgmt
Synonyms : MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase; O-6-alkylguanine-DNA alkyltransferase; O-6-methylguanine-DNA-alkyltransferase; 6-O-methylguanine-DNA methyltransferase; AGT; Agat; AI267024; MGC107020
Gene ID : 17314
mRNA Refseq : NM_008598
Protein Refseq : NP_032624
UniProt ID : P26187
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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