Recombinant Mouse Prmt5 Protein, Myc/DDK-tagged

Cat.No. : Prmt5-5133M
Product Overview : Purified recombinant protein of mouse full-length protein arginine N-methyltransferase 5 (Prmt5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation and the assembly of small nuclear ribonucleoproteins. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 72.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Prmt5 protein arginine N-methyltransferase 5 [ Mus musculus (house mouse) ]
Official Symbol : Prmt5
Synonyms : PRMT5; protein arginine N-methyltransferase 5; SKB1 homolog; Jak-binding protein 1; shk1 kinase-binding protein 1 homolog; histone-arginine N-methyltransferase PRMT5; Jbp1; Skb1
Gene ID : 27374
mRNA Refseq : NM_013768
Protein Refseq : NP_038796
UniProt ID : Q8CIG8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any ongoing clinical trials targeting PRMT5? 05/31/2021

Yes, there are ongoing clinical trials investigating the efficacy of PRMT5 inhibitors in various cancer types.

How does PRMT5 affect cellular differentiation? 12/10/2019

PRMT5 influences cellular differentiation by regulating the expression of genes involved in the process.

Can PRMT5 inhibitors be used in combination therapies? 07/05/2018

Yes, there is interest in exploring combination therapies involving PRMT5 inhibitors with other anticancer agents to enhance treatment efficacy.

How does PRMT5 contribute to epigenetic regulation? 04/26/2016

PRMT5 methylates histone proteins, leading to changes in chromatin structure and gene expression, thus playing a crucial role in epigenetic regulation.

How does PRMT5 influence neurodegenerative diseases? 01/04/2016

PRMT5 has been implicated in neurodegenerative diseases, and understanding its role may provide insights into developing therapies for conditions like Alzheimer's and Parkinson's disease.

Customer Reviews (3)

Write a review
Reviews
02/18/2023

    Great performance in ELISA.

    11/01/2018

      Its purity and functionality ensure precise and reproducible results, enabling me to achieve my research objectives with confidence.

      10/30/2016

        The PRMT5 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

        Ask a Question for All Prmt5 Products

        Required fields are marked with *

        My Review for All Prmt5 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends