Recombinant Mouse Prmt5 Protein, Myc/DDK-tagged

• Cat.No.: Prmt5-5133M
• Product Overview: Purified recombinant protein of mouse full-length protein arginine N-methyltransferase 5 (Prmt5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation and the assembly of small nuclear ribonucleoproteins. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 72.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prmt5 protein arginine N-methyltransferase 5 [ Mus musculus (house mouse) ]
• Official Symbol: Prmt5
• Synonyms: PRMT5; protein arginine N-methyltransferase 5; SKB1 homolog; Jak-binding protein 1; shk1 kinase-binding protein 1 homolog; histone-arginine N-methyltransferase PRMT5; Jbp1; Skb1
• Gene ID: 27374
• mRNA Refseq: NM_013768
• Protein Refseq: NP_038796
• UniProt ID: Q8CIG8