Recombinant Mouse Siglec1 Protein, Myc/DDK-tagged

• Cat.No.: Siglec1-5876M
• Product Overview: Purified recombinant protein of mouse full-length sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 184 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin [ Mus musculus (house mouse) ]
• Official Symbol: Siglec1
• Synonyms: SIGLEC1; sialic acid binding Ig-like lectin 1, sialoadhesin; sialoadhesin; SER; sheep erythrocyte receptor; sialic acid-binding Ig-like lectin 1; Sn; Cd169; Siglec-1
• Gene ID: 20612
• mRNA Refseq: NM_011426
• Protein Refseq: NP_035556
• UniProt ID: Q62230