Recombinant Mouse Stat3 protein, His-tagged

• Cat.No.: Stat3-8593M
• Product Overview: Recombinant Mouse Stat3(Thr346~Glu552) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Thr346~Glu552
• Form: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Molecular Mass: 24.8kDa
• AA Sequence: MGHHHHHHSG SEF- TTKVR LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM PNAWASILWY NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS GCQITWAKFC KE
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Stat3 signal transducer and activator of transcription 3 [ Mus musculus ]
• Official Symbol: Stat3
• Synonyms: STAT3; signal transducer and activator of transcription 3; acute phase response factor; acute-phase response factor; Aprf; AW109958; 1110034C02Rik
• Gene ID: 20848
• mRNA Refseq: NM_011486
• Protein Refseq: NP_035616
• UniProt ID: Q6GU23
• Chromosome Location: 11 D; 11 63.82 cM
• Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: CCR5 chemokine receptor binding; DNA binding; DNA binding; calcium ion binding; glucocorticoid receptor binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor binding; transcription regulatory region DNA binding