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Recombinant Mouse Ube2l3 Protein, Myc/DDK-tagged

Cat.No. : Ube2l3-6792M
Product Overview : Purified recombinant protein of mouse full-length ubiquitin-conjugating enzyme E2L 3 (Ube2l3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 18.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ube2l3 ubiquitin-conjugating enzyme E2L 3 [ Mus musculus (house mouse) ]
Official Symbol : Ube2l3
Synonyms : UBE2L3; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme E2 L3; ubiquitin-protein ligase L3; ubiquitin carrier protein L3; ubiquitin-conjugating enzyme 7; UbcM4; Ubce7; C79827; MGC118100
Gene ID : 22195
mRNA Refseq : NM_009456
Protein Refseq : NP_033482
UniProt ID : P68037

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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