Recombinant Mouse Wdr5 Protein, MYC/DDK-tagged


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Recombinant Mouse Wdr5 Protein, MYC/DDK-tagged

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Cat.No. : Wdr5-1016M
Product Overview : Purified recombinant protein of full-length mouse WD repeat domain 5 (Wdr5), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : Contributes to histone modification (By similarity). May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (By similarity). As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 (By similarity). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (By similarity). May regulate osteoblasts differentiation (PubMed:11551928). In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity).
Source : HEK293T
Species : Mouse
Molecular Mass : 36.6 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Wdr5 WD repeat domain 5 [ Mus musculus (house mouse) ]
Official Symbol : Wdr5
Synonyms : Wdr5; WD repeat domain 5; Big; Big-3; AA408785; AA960360; 2410008O07Rik; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; WD repeat-containing protein BIG-3
Gene ID : 140858
mRNA Refseq : NM_080848
Protein Refseq : NP_543124
UniProt ID : P61965
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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