Recombinant Rat Fgf18 protein, His/S-tagged Fgf18-185R

Recombinant Rat Fgf18 protein, His/S-tagged

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Cat.No. : Fgf18-185R Optional Service: Optional requirements on this protein
Product Overview : Recombinant Rat Fgf18 fused with His/S tag was expressed in E. coli.
Description : FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Source : E. coli
Species : Rat
Tag : His/S
Form : Lyophilized from sterile PBS, pH 7.4
Purity : > 95 % as determined by SDS-PAGE
Storage : Store at -70 centigrade. Avoid repeated freeze/thaw cycles.
Gene Name : Fgf18 fibroblast growth factor 18 [ Rattus norvegicus ]
Official Symbol : Fgf18
Synonyms : FGF18; fibroblast growth factor 18; FGF-18;
Gene ID : 29369
mRNA Refseq : NM_019199
Protein Refseq : NP_062072
UniProt ID : O88182
Chromosome Location : 10q12
Pathway : Endochondral Ossification, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; Pathways in cancer, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem;
Function : fibroblast growth factor receptor binding; growth factor activity; type 1 fibroblast growth factor receptor binding; type 2 fibroblast growth factor receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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