"Fgf23" Related Products

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Recombinant Rat Fgf23 protein, His-tagged

Cat.No.: Fgf23-493R
Product Overview: Recombinant Rat Fgf23(aa 25-251) fused with His tag was expressed in E. coli.
Description: FGF23 is a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).
Source: E. coli
Species: Rat
Tag: His
Form: 20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
Molecular Mass: 29.6 Kd
AA Sequence: YSDTSPLLGS NWGSLTHLYT ATARNSYHLQ IHRDGHVDGTPHQTIYSALM ITSEDAGSVV IIGAMTRRFL CMDLRGNIFGSYHFSPENCR FRQWTLENGY DVYLSPKHHY LVSLGRSKRIFQPGTNPPPF SQFLARRNEV PLLHFYTARP RRHTRSAEDPPERDPLNVLK PRPRATPIPV SCSRELPSAE EGGPAASDPLGVLRRGRGDA RRGAGGTDRC RPFPRFV
Storage: Long term: -80 centigrade; Short term: -20 centigrade. Avoid freeze-thaw cycles.
Gene Name: Fgf23 fibroblast growth factor 23 [ Rattus norvegicus ]
Official Symbol: Fgf23
Synonyms: FGF23; fibroblast growth factor 23; FGF-23;
Gene ID: 170583
mRNA Refseq: NM_130754
Protein Refseq: NP_570110
MIM:
UniProt ID: Q8VI82
Chromosome Location: 4q42
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1c and Klotho ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem
Function: fibroblast growth factor receptor binding; fibroblast growth factor receptor binding; growth factor activity; type 1 fibroblast growth factor receptor binding; type 1 fibroblast growth factor receptor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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