Recombinant Rhesus macaque CD4 Protein, Fc-tagged

• Cat.No.: CD4-159R
• Product Overview: Recombinant Rhesus macaque CD4 protein with Fc tag was expressed in HEK293.

Specification

• Description: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
• Source: HEK293
• Species: Rhesus macaque
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 67 kDa
• Protein length: 458
• AA Sequence: MNRGIPFRHLLLVLQLALLPAVTQG KKVVLGKKGDTVELTCNASQKKNTQ FHWKNSNQIKILGIQGSFLTKGPSK LSDRADSRKSLWDQGCFSMIIKNLK IEDSDTYICEVENKKEEVELLVFGL TANSDTHLLEGQSLTLTLESPPGSS PSVKCRSPGGKNIQGGRTISVPQLE RQDSGTWTCTVSQDQKTVEFKIDIV VLAFQKASSTVYKKEGEQVEFSFPL AFTLEKLTGSGELWWQAERASSSKS WITFDLKNKEVSVKRVTQDPKLQMG KKLPLHLTLPQALPQYAGSGNLTLA LEAKTGKLHQEVNLVVMRATQFQEN LTCEVWGPTSPKLTLSLKLENKGAT VSKQAKAVWVLNPEAGMWQCLLSDS GQVLLESNIKVVPTWPTPVQPMALI VLGGVAGLLLFTGLGIFFCVRCRHR RRQAERMSQIKRLLSEKKTCQCPHR FQKTCSPI
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: CD4 CD4 molecule [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CD4
• Synonyms: CD4; CD4 molecule; T-cell surface glycoprotein CD4; CD4 antigen; T-cell surface antigen T4/Leu-3
• Gene ID: 713807
• mRNA Refseq: NM_001042662
• Protein Refseq: NP_001036127
• UniProt ID: P16003

Reviews

01/08/2031

The CD4 proteins purchased from your company is suitable for ELISA.

02/06/2023

Protein products are put into experiments with good effect and reliable experimental results.

01/22/2022

The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

Q&As

What is the connection between CD4 and glycoprotein GP120?

CD4 binds to glycoprotein GP120.

Where is CD4 primarily expressed?

CD4 is mainly expressed in T cells and thymocytes.

Where is CD4 localized?

CD4 is localized in the cell membrane.