FGFR1 Protein, fibroblast growth factor receptor 1

FGFR1

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FGFR1

Official Full Name fibroblast growth factor receptor 1
Background Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome.
Synonyms FLG; FGFR1; fibroblast growth factor receptor 1; CEK; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; FLJ99988; bFGF-R-1; OTTHUMP00000190874; OTTHUMP00000190875; OTTHUMP00000190876; OTTHUMP00000190877; OTTHUMP00000190879; OTTHUMP00000190880; OTTHUMP00000190881; OTTHUMP00000190885; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; H2; H3; H4; H5; Basic fibroblast growth factor receptor 1; N sam tyrosine kinase; Protein tyrosine kinase; Tyrosylprotein kinase; Hydroxyaryl protein kinase; Heparin binding growth factor receptor
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • NSO
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • His
    • Fc
    • Flag
    • GST
    • S
    • T7
    • Myc
    • N/A
    • Strep
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGFR1-384H Recombinant Human FGFR1 protein, Strep-tagged HEK293 Strep
    Human FGFR1-715H Recombinant Human FGFR1 Protein, His-tagged Insect Cell His
    Human FGFR1-01H Recombinant Human Fibroblast Growth Factor Receptor 1, Fc-tagged Insect Cell Fc
    Human FGFR1-111H Recombinant Human FGFR1 protein, T7/His-tagged E.coli T7/His
    Human FGFR1-1133H Recombinant Human FGFR1 Protein, His-tagged HEK293 His
    Human FGFR1-138H Recombinant Human FGFR1, Fc-His tagged Human Cell Fc/His
    Human FGFR1-1405H Recombinant Human FGFR1 (Active), GST-tagged Sf9 Insect Cell GST
    Human FGFR1-18H Recombinant Human FGFR1 protein, His-tagged HEK293 His
    Human FGFR1-2054H Recombinant Human FGFR1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FGFR1-2056H Recombinant Human FGFR1 Protein, His-tagged Insect Cell His
    Human FGFR1-207H Recombinant Human FGFR1 Mammalian Cell His
    Human FGFR1-208H Recombinant Human FGFR1 protein, DDK/His-tagged HEK293 DDK/His
    Human FGFR1-210H Recombinant Human FGFR1 protein, DDK/His-tagged HEK293 DDK/His
    Human FGFR1-211H Recombinant Human FGFR1 protein, His-tagged Insect Cell His
    Human FGFR1-236H Recombinant Human FGFR1 Protein, His & GST-tagged Insect Cell His/GST
    Human FGFR1-2765HCL Recombinant Human FGFR1 cell lysate Human Cell N/A
    Human FGFR1-28834TH Recombinant Human FGFR1 N/A
    Human FGFR1-28886TH Recombinant Human FGFR1 N/A
    Human FGFR1-28890TH Recombinant Human FGFR1 N/A
    Human FGFR1-312H Recombinant Human FGFR1, GST-tagged, Active Sf9 Insect Cell GST
    Human FGFR1-316H Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged HEK293 His
    Human FGFR1-4121H Recombinant Human FGFR1 Protein, GST/His-tagged Insect Cell GST/His
    Human FGFR1-4122H Recombinant Human FGFR1 Protein Wheat Germ N/A
    Human FGFR1-4123H Recombinant Human FGFR1 Protein, GST-tagged Wheat Germ GST
    Human FGFR1-45H Recombinant Human FGFR1 protein, Flag-tagged, Biotinylated Insect Cell Flag
    Human FGFR1-476HCL Recombinant Human FGFR1 cell lysate Insect Cell N/A
    Human FGFR1-4843H Recombinant Human Fibroblast Growth Factor Receptor 1, GST-tagged Sf9 Insect Cell GST
    Human FGFR1-485H Recombinant Human Fibroblast Growth Factor Receptor 1(IIIb) NSO N/A
    Human FGFR1-486H Recombinant Human Fibroblast Growth Factor Receptor 1(IIIc) NSO N/A
    Human FGFR1-487H Recombinant Human Fibroblast Growth Factor Receptor 1 Beta NSO N/A
    Human FGFR1-498H Recombinant Human FGFR1, Fc Chimera HEK293 Fc
    Human FGFR1-5417H Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged Insect Cell his
    Human FGFR1-605H Recombinant Human FGFR1, His-tagged, Biotinylated Human Cell His
    Human FGFR1-606H Recombinant Human FGFR1, Fc-tagged, Biotinylated Human Cell Fc
    Human FGFR1-697H Recombinant Human FGFR1 Protein, Fc Chimera NS0 Fc
    Human FGFR1-8305H Recombinant Human FGFR1 NS0 N/A
    Mouse FGFR1-2133MCL Recombinant Mouse FGFR1 cell lysate Human Cell N/A
    Mouse Fgfr1-4015M Recombinant Mouse Fgfr1, Fc tagged Human Cell Fc
    Mouse Fgfr1-4016M Recombinant Mouse Fgfr1, His tagged Human Cell His
    Rat Fgfr1-1800R Recombinant Rat Fgfr1 protein, His & S-tagged E.coli His/S
    Rat FGFR1-2338R Recombinant Rat Fgfr1 protein, His/T7-tagged E.coli His/T7
    Rat Fgfr1-2339R Recombinant Rat Fgfr1 protein, His-tagged HEK293 His
    Cynomolgus Monkey FGFR1-1171CCL Recombinant Cynomolgus FGFR1 cell lysate Human Cell N/A
    Cynomolgus Monkey FGFR1-55C Recombinant Cynomolgus FGFR1, Fc tagged Mammalian Cell Fc
    Cynomolgus Monkey FGFR1-67C Recombinant Cynomolgus FGFR1 protein, His-tagged HEK293 His
    Rhesus Macaque FGFR1-1704R Recombinant Rhesus monkey FGFR1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque FGFR1-66C Recombinant Rhesus FGFR1 protein, His-tagged HEK293 His
    Rhesus Macaque FGFR1-8817C Recombinant Rhesus FGFR1 protein, Fc-tagged HEK293 Fc
    Chicken FGFR1-7059C Recombinant Chicken FGFR1 Mammalian Cell His
    Kit-1557 U2OS FGFR1 Bioassay Kit N/A
    Kit-1590 FGFR1 Functional Assay Kit N/A

    FGFR1 involved in several pathways and played different roles in them. We selected most pathways FGFR1 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGFR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MKNK2A; MEF2CB; RPS6KA3; MRAS; PAK2; PAK2A; ACVR1C; KRAS; STMN1; MAP4K2
    Ras signaling pathway ETS1; NF1; ARF6; FGF14; RAC2; RASAL2; FGF7; RAP1A; CSF1; PLA2G12A
    Rap signaling pathway VASP; MAP2K3; RALGDS; PIK3R2; GNAS; FGF20; RAPGEF6; LPAR4; FGF19; MAP2K1
    PIK-Akt signaling pathway MLST8; TLR2; COL6A5; GNB4; IL6R; GNG2; PGF; YWHAG; TLR4; IFNA21
    Adherens junction FYNB; WASF3; FER; ACP1; MAP3K7; PVRL1; TCF7L1A; SMAD3; WASF1; SMAD2
    Signaling pathways regulating pluripotency of stem cells MAPK1; LHX5; MAPK12; WNT5B; Fzd4; PIK3R1; INHBB; STAT3; IGF1; WNT8B
    Regulation of actin cytoskeleton ITGAL; MYL9A; PIP5K1C; PTK2AB; CFL2; ITGA5; HRASB; RHOAC; INSB; ITGA8
    Pathways in cancer ITGA6; FGF1; SLC2A1; WNT5B; FLT3; FZD1; AXIN2; RARA; CDH1; MSH3
    Proteoglycans in cancer HCLS1; Fzd4; MAPK12; WNT10B; SLC9A1; ERBB4; IGF2; VTN; ARAF; PPP1R12B
    Prostate cancer CREB3L1; ERBB2; PDGFRB; PDGFA; HSP90AB1; SMARCC2; INS2; IKBKG; PDGFC; PDGFB
    Melanoma Pdgfa&Pdgfb; FGF20; FGF17; Fgf15; FGF21; KRAS; MET; FGF16; ARAF; MITF
    Central carbon metabolism in cancer PKM; PIK3R1; KRAS; PIK3R3; MAP2K2; PIK3R5; PIK3CA; MAPK1; FLT3; ERBB2

    FGFR1 has several biochemical functions, for example, ATP binding, cell adhesion molecule binding, fibroblast growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGFR1 itself. We selected most functions FGFR1 had, and list some proteins which have the same functions with FGFR1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding P2RX8; ADCY9; ABCC12; PIP4K2A; ABCC11; BRIP1; CKM; AGK; GLUD1; FGR
    cell adhesion molecule binding NRXN3; PTBP3; CD1d1; PVRL4; CD226; VCAM1; CD200; PTPRD; NRXN1; CXADR
    fibroblast growth factor binding GLG1; FIBPA; CEP57; CXCL13; SCN5A; FGFBP3; PTPRZ1; TGFBR3; FGFR3; RPS2
    fibroblast growth factor-activated receptor activity FGFR2; FGFR3; FGFRL1; FGFR4; FGFR1; FGFR1A; FGFR1B
    glycoprotein binding APOH; Itgam&Itgb2; LACRT; LDLR; CSNK1D; Shh; SERPINA1E; SELP; F7; RGMA
    heparin binding SAA1; COMP; Itgam&Itgb2; VEGFAB; CYR61; KAL1; PRG2; HBEGF; BMP4; CTGF
    identical protein binding TPRGL; DYNLT1F; CLDN15; VCP; CNTN2; LTBR; UHRF1; KCNJ10; DYNLT3; ABCD1
    protein binding TRAM1; SZT2; TET2; BLOC1S1; GTF2H4; ACTG1; DYNLL1; C12orf68; GRIK3; HPS6
    protein complex binding MTHFR; RRAS; KHDRBS1; ING2; TXN2; EP300; ERCC6; KRT8; NCKAP1; TMED10
    protein homodimerization activity FIGF; BAXB; APOA4; UGT1A6A; IDH1; OXCT1; LHPP; SMAD3; HPGDS; MYH9
    protein tyrosine kinase activity ERBB4; EPHA4B; EPHB3A; NTRK3A; FGFR4; PTK7; KITB; BCR; KIAA1804; FYNB

    FGFR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGFR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGFR1.

    PLCG1; HTR1A; FGF2

    Stachowiak, MK; Birkaya, B; et al. "Nuclear FGF Receptor-1 and CREB Binding Protein: An Integrative Signaling Module". JOURNAL OF CELLULAR PHYSIOLOGY 230:989-1002(2015).
    Ambrosini, S; Sarchielli, E; et al. FIBROBLAST GROWTH FACTOR AND ENDOTHELIN-1 RECEPTORS MEDIATE THE RESPONSE OF HUMAN STRIATAL PRECURSOR CELLS TO HYPOXIA. NEUROSCIENCE 289:123-133(2015).

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