il15
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  • Official Full Name
  • interleukin 15
  • Background
  • Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.
  • Synonyms
  • IL15; MGC9721; Interleukin-15 precursor; OTTHUMP00000164617; interleukin 15; IL-15
Cat.#:IL15-01RTag:His
Source (Host):YeastSpecies:Rhesus Monkey
Product nameRecombinant Rhesus Monkey IL15 Protein, His-tagged
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Cat.#:IL15-272HTag:Fc/Avi
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human IL15 protein, Fc/Avi-tagged, Biotinylated
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Cat.#:IL15-321HTag:
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human IL15 Protein (Asn 49 - Ser 162)
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Cat.#:IL15-382HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15 Protein (Asn49-Ser162)
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Cat.#:IL15-004HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15 Protein, His-tagged
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Cat.#:IL15-483HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 15
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Cat.#:Il15-484MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 15
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Cat.#:Il15-001HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Il15, HIgG1 Fc-tagged, mutant
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Cat.#:Il15-002HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Il15, MIgG2a Fc-tagged
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Cat.#:IL15-006HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL15, HIgG1 Fc-tagged
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Cat.#:IL15-125HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15 protein
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Cat.#:IL15-25HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15
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Cat.#:IL15-270HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL15, StrepII-tagged
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Cat.#:IL15-271HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL15 protein
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Cat.#:IL15-28238THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15, His-tagged
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Cat.#:IL15-306HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15, His-tagged
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Cat.#:IL15-330HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL15, Fc-tagged
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Cat.#:IL15-45HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL15 protein, His-tagged
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Cat.#:IL15-8119MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IL15 Protein
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Cat.#:IL15-3028RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IL15 Protein
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Cat.#:IL15-2232RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IL15 Protein, His-tagged
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Cat.#:IL15-20CTag:
Source (Host):YeastSpecies:Chicken
Product nameRecombinant Chicken IL-15
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Cat.#:IL15-6140CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL15
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Cat.#:IL15-863RTag:His
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit IL15 protein, His-tagged
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Cat.#:IL15-3624ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IL15
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Cat.#:IL15-1099FTag:
Source (Host):E. coliSpecies:Feline
Product nameRecombinant Feline IL15
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Cat.#:IL15-263STag:N/A
Source (Host):YeastSpecies:Pig
Product nameRecombinant Swine IL15
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Cat.#:IL15-80GTag:
Source (Host):YeastSpecies:Guinea Pig
Product nameRecombinant Guinea Pig IL-15
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Cat.#:IL15-859CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle IL15 protein, His-tagged
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Cat.#:Il15-860GTag:His/S
Source (Host):E. coliSpecies:Guinea pig
Product nameRecombinant Guinea pig Il15 protein, His & S-tagged
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Cat.#:IL15-861STag:His
Source (Host):E. coliSpecies:Sheep
Product nameRecombinant Sheep IL15 protein, His-tagged
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Cat.#:IL15-532HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 15, His-tagged
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Cat.#:Il15-423MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 15, His-tagged
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Cat.#:Il15-533MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 15, His-tagged
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Cat.#:Il15-739MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 15, His-tagged
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Cat.#:IL15-24HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin-15
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Cat.#:Il15-69MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 15
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Cat.#:Il15-231RTag:N/A
Source (Host):Sf 21 Insect cellsSpecies:Rat
Product nameRecombinant Rat Interleukin 15
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Cat.#:Il15-88RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Interleukin 15
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Cat.#:IL15-235BTag:N/A
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine Interleukin 15
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Cat.#:IL15-253ETag:N/A
Source (Host):YeastSpecies:Equine
Product nameRecombinant Equine Interleukin 15
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Cat.#:IL15-80PTag:N/A
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Porcine Interleukin-15
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Cat.#:IL15-5248HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IL15 293 Cell Lysate
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Cat.#:IL15-4329HGTag:
Source (Host):E. coliSpecies:Human
Product nameGMP Recombinant Human IL15 protein
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Cat.#:IL15-147HTag:
Source (Host):Species:Human
Product nameHuman Interleukin-15(rDNA derived) Reference standard
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Involved Pathway

IL15 involved in several pathways and played different roles in them. We selected most pathways IL15 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
MET; IL2RGA; IL4R; BMPR2B; CXCL12; TNFRSF12A; Cxcl15; CXCL10; IL20; TNFSF14
Jak-STAT signaling pathway
IFNA8; PTPN2; IL12A; IFNA1; STAT4; GHR; IFNPHI1; CRFB2; STAM; Ifnlr1
TNF signaling pathway
TRADD; IKBKB; MAP3K7IP3; IL6; Casp3; CXCL10; LIF; MAPK8; PIK3CD; NFKB1
Intestinal i
TGFB1; MHC2DAB; ICOSLG; ICOS; H2-AB1; IL5; HLA-DRB3; MHC2A; BMA1; MHC2DCB
ne network for IgA production
Icosl; HLA-DOA; CD40; CD40LG; CCR10; HLA-DMA; CD86; CXCL12; HLA-DRB1; HLA-DPB1
HTLV-I infection
FZD6; CANX; NFKB1; AKT2; WNT1; CD3D; GSK3B; IL1R1; Pdgfa&Pdgfb; MSX1
Herpes simplex infection
HLA-B; HLA-E; MAPK9; HLA-DMA; PTPN11B; MAPK8B; GTF2I; HLA-DPA1; IFNPHI1; IFNA4
Rheumatoid arthritis
ATP6V1C1; MMP1A; CXCL1; FOS; ATP6V0A1; CXCL12; LTB; IFNG; HLA-DRB4; ATP6V0C

Protein Function

IL15 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL15 itself. We selected most functions IL15 had, and list some proteins which have the same functions with IL15. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein SP100; IL23; IFNA7; BMP6; FAM3B; TNFSF13; SECTM1; IL37; NAMPT; Ifna11
Function cytokine receptor binding
Related Protein IFNA13; MIF; IL17D; IFNPHI3; IFNT2; IL21; IFNPHI4; IFNA14; IL15; IFN-a
Function protein binding
Related Protein PKMYT1; SKP1; SPRED2; DLL4; EEF2; ATP6V0A1; TNKS2; C1D; ISG15; SAP30BP

Interacting Protein

IL15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL15 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL15.
IL2RB; IL15RA; STAT5B; TRAF3; ZNRD1

IL15 Related Articles

Krabben, A; Huizinga, TWJ; et al. Biomarkers for Radiographic Progression in Rheumatoid Arthritis. CURRENT PHARMACEUTICAL DESIGN 21:147-169(2015).
Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).