ror1
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  • Official Full Name
  • receptor tyrosine kinase-like orphan receptor 1
  • Background
  • ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringl
  • Synonyms
  • ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase receptor-related 1; neurotrophic tyrosine kinase, receptor-related 1; dJ537F10.1; MGC99659
Cat.#:ROR1-1810HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 Protein, His-Avi-tagged, Biotinylated
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Cat.#:ROR1-1815HATag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged, APC labeled
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Cat.#:ROR1-1815HPTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged, R-PE labeled
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Cat.#:Ror1-192MATag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ror1 protein, Fc-tagged, APC labeled
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Cat.#:Ror1-192MPTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ror1 protein, Fc-tagged, R-PE labeled
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Cat.#:ROR1-198HATag:His
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human ROR1 protein, His-tagged, APC labeled
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Cat.#:ROR1-198HPTag:His
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human ROR1 protein, His-tagged, R-PE labeled
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Cat.#:ROR1-312HTag:Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 Protein (Gln 30 - Glu 403), Avi-tagged, Biotinylated
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Cat.#:ROR1-387HATag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged, APC labeled
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Cat.#:ROR1-387HPTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged, R-PE labeled
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Cat.#:ROR1-595HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 Protein (Met1-Glu403), Biotinylated
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Cat.#:ROR1-512HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ROR1 Protein, His-tagged
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Cat.#:Ror1-513MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ror1 Protein, His-tagged
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Cat.#:ROR1-1811HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc & Avi-tagged, Biotinylated
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Cat.#:ROR1-1812HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, His-tagged
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Cat.#:ROR1-1813HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, His-tagged
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Cat.#:ROR1-1814HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, His-tagged
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Cat.#:ROR1-1815HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged
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Cat.#:ROR1-198HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1, His-tagged
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Cat.#:ROR1-232HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human ROR1, GST-tagged
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Cat.#:ROR1-2358HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ROR1, His-tagged
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Cat.#:ROR1-30958THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ROR1
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Cat.#:ROR1-387HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Fc-tagged
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Cat.#:ROR1-540HTag:Fc
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ROR1, His-GST tagged
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Cat.#:ROR1-666HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human ROR1, Fc-tagged, Biotinylated
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Cat.#:ROR1-755HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human ROR1 Protein, DDK/His-tagged
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Cat.#:ROR1-756HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human ROR1 Protein, DDK/His-tagged
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Cat.#:ROR1-7814HTag:Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 protein, Avi-tagged
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Cat.#:ROR1-88HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ROR1 protein, T7/His-tagged
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Cat.#:ROR1-14377MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ROR1 Protein
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Cat.#:Ror1-192MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ror1, Fc-tagged
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Cat.#:Ror1-193MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ror1, His-tagged
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Cat.#:Ror1-1816RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ror1 protein, His-tagged
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Cat.#:ROR1-6078CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ROR1
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Cat.#:ROR1-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR1 cell lysate
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Cat.#:ROR1-002HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ROR1 cell lysate
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Involved Pathway

ROR1 involved in several pathways and played different roles in them. We selected most pathways ROR1 participated on our site, such as Beta-catenin independent WNT signaling, Nuclear Receptors, PCP/CE pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ROR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Beta-catenin independent WNT signaling
AP2M1; ROR2; PRICKLE1; AGO2; PRICKLE1B; AP2S1; DVL1; DVL2; MOV10; RYK
Nuclear Receptors
NR2E1; NR1D2; NR2C2; NR0B1; NR1I3; NR2F1A; RORAA; RARGB; NR2F1; NR5A1
PCP/CE pathway
RYK; ROR2; PRICKLE1; PRICKLE1B; ROR1
Signal Transduction
PRC1B; NEDD8; ARHGAP29; ARHGAP19; NRP2A; TLE2; NOTUM1A; OR2AP1; PROKR2; GPR132B
Signaling by Wnt
TNKS2; KLHL12; LGR4; CSNK1G2; SOX7; TMED5; LEO1; GPR177; HECW1; RSPO4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
ROR1; ROR2

Protein Function

ROR1 has several biochemical functions, for example, ATP binding, Wnt-protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ROR1 itself. We selected most functions ROR1 had, and list some proteins which have the same functions with ROR1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein STK35; UBE2G1A; VPS4A; ASNS; NARS; IQCA1; ROCK2; RHOBTB3; TPK1; UBE2G1
Function Wnt-protein binding
Related Protein SFRP2; FZD9B; ROR1; GPR177; FZD5; FZD3; WLS; LRP2A; Fzd4; SMO
Function protein binding
Related Protein CEP68; KCNJ3; SCFD1; HIST1H1C; GATA6; ATF4; LRRC3; NOTCH1; CNOT3; CCPG1
Function transmembrane receptor protein tyrosine kinase activity
Related Protein KDRL; ROR1; RYK; TRIM27; NTRK3A; RET; NPTNB; NTRK2B; NTRK1; DDR2

Interacting Protein

ROR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ROR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ROR1.
SRC; Src; EGFR

ROR1 Related Articles

Zhang, SP; Cui, B; et al. Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:17266-17271(2014).
Hojjat-Farsangi, M; Moshfegh, A; et al. The receptor tyrosine kinase ROR1-An oncofetal antigen for targeted cancer therapy. SEMINARS IN CANCER BIOLOGY 29:21-31(2014).