SELP
-
Official Full Name
selectin P (granule membrane protein 140kDa, antigen CD62)
-
Overview
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. -
Synonyms
SELP; selectin P (granule membrane protein 140kDa, antigen CD62); GRMP, selectin P (granule membrane protein 140kD, antigen CD62); P-selectin; CD62; CD62P; GMP140; PADGEM; PSEL; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein; GRMP; LECAM3; FLJ45155;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Cynomolgus Monkey
- Human
- Mouse
- Mus musculus (Mouse)
- Ovis aries (Sheep)
- Rabbit
- Rat
- Rattus norvegicus (Rat)
- Rhesus
- Zebrafish
- CHO
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Human cells
- Mammalian Cell
- Mammalian cells
- Avi
- His
- C
- 6His
- hFc
- Fc
- Fc|His
- Myc
- His (Fc)
- His\Avi
- His|T7
- human|IgG1|Fc
- DDK
- Myc|DDK
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SELP-473H | Active Recombinant Human SELP protein, hFc-tagged | HEK293 | hFc | Met1-Ala771 | |
Human | SELP-457H | Active Recombinant Human SELP, Fc Chimera | HEK293 | Fc/His | ||
Human | SELP-2585H | Recombinant Human SELP protein, His & T7-tagged | E.coli | His/T7 | Arg198~Asn432 (Accession # P16109) | |
Human | SELP-458H | Recombinant Human SELP | HEK293 | N/A | ||
Human | SELP-2584H | Recombinant Human SELP protein, His-tagged | E.coli | His | Lys58~Glu195 (Accession # P16109) | |
Human | SELP-208H | Recombinant Human SELP protein, Fc-tagged | HEK293 | human/IgG1/Fc | Trp42-Ala771 | |
Human | SELP-8327H | Recombinant Human SELP | CHO | N/A | ||
Human | SELP-27886TH | Recombinant Human SELP | N/A | |||
Human | SELP-1674H | Recombinant Human SELP | Mammalian cells | N/A | ||
Human | SELP-282H | Recombinant Human selectin P, His-tagged | E.coli | His | ||
Human | SELP-474H | Recombinant Human SELP protein, His-tagged | HEK293 | His | Trp42-Ala771 | |
Human | SELP-1598HCL | Recombinant Human SELP cell lysate | Human Cell | N/A | ||
Human | SELP-0648H | Recombinant Human SELP protein, Fc-tagged | HEK293 | Fc | Trp42-Ala771 | |
Human | SELP-1528H | Recombinant Human SELP protein, hFc-Myc-tagged | HEK293 | hFc-Myc | 42-771aa | |
Human | SELP-404H | Recombinant Human SELP Protein, Fc-tagged | HEK293 | Fc | 830 | |
Human | SELP-3078H | Recombinant Human SELP Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | SELP-2185H | Recombinant Human SELP protein, His-tagged | HEK293 | His | Met1-Ala771 | |
Human | SELP-4478H-B | Recombinant Human SELP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | SELP-387H | Recombinant Human SELP Protein (Trp42-Aal771), C-hFc-tagged | HEK293 | C-hFc | Trp42-Aal771 | |
Human | SELP-151H | Recombinant Human SELP Protein, His-tagged | Human cells | His | ||
Human | SELP-6261H | Recombinant Human SELP Protein (Lys58-Glu195), His tagged | E.coli | His | Lys58-Glu195 | |
Human | SELP-3364H | Recombinant Human SELP protein, His and hFc-tagged | HEK293 | His and hFc | Lys58~Glu195 | |
Human | SELP-5085H | Recombinant Human SELP Protein (Met1-Ala771), C-His tagged | Mammalian cells | C-His | Met1-Ala771 | |
Human | SELP-403H | Recombinant Human SELP Protein, His-tagged | HEK293 | His | 830 | |
Human | SELP-4478H | Recombinant Human SELP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | SELP-598H | Recombinant Human SELP Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | SELP-109HB | Recombinant Human SELP protein, His-Avi-tagged, Biotinylated | HEK293 | His-Avi | Trp 42-Ala 771 | |
Human | SELP-109H | Recombinant Human SELP protein, His-Avi-tagged | HEK293 | His-Avi | It contains Trp 42 - Ala 771. | |
Mouse | SELP-905M | Active Recombinant Mouse SELP protein, hFc-tagged | HEK293 | hFc | Met1-Ala709 | |
Mouse | Selp-2586M | Recombinant Mouse Selp protein, His-tagged | E.coli | His | Val58~Ala259 (Accession # Q01102) | |
Mouse | SELP-305M | Active Recombinant Mouse SELP protein, His-tagged | HEK293 | His | Met1-Ala709 | |
Mouse | Selp-8340M | Recombinant Mouse Selp | Mammalian cells | N/A | ||
Mouse | Selp-534M | Recombinant Mouse Selp, Fc-tagged | Human Cell | Fc | Met1-Ala709 | |
Mouse | SELP-972MCL | Recombinant Mouse SELP cell lysate | Human Cell | N/A | ||
Mouse | Selp-5757M | Recombinant Mouse Selp Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | SELP-306M | Recombinant Mouse SELP(Trp42Ala709) Protein, C-Avi-6*His-tagged, Biotinylated | HEK293 | Avi-His | ||
Mouse | Selp-05M | Recombinant Mouse Selp Protein, C-Avi-6His tagged, Biotinylated | Human Cell | C-Avi-6His | Trp42-Ala709 | |
Mouse | SELP-177M | Recombinant Mouse SELP Protein, His\Avi-tagged | Human Cell | His\Avi | ||
Mouse | Selp-10612M-B | Recombinant Mouse Selp Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Selp-10612M | Recombinant Mouse Selp Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SELP-1114R | Active Recombinant Rat SELP protein(Met1-Gln700), hFc-tagged | HEK293 | C-hFc | Met1-Gln700 | |
Rat | Selp-2587R | Recombinant Rat Selp protein, His-tagged | E.coli | His | Ala58~Cys158 (Accession # P98106) | |
Rat | Selp-563R | Recombinant Rat Selp, His-tagged | Human Cell | His | Met1-Gln700 | |
Rat | SELP-5310R | Recombinant Rat SELP Protein | Mammalian Cell | His | ||
Rat | SELP-001RCL | Recombinant Rat SELP cell lysate | Human Cell | N/A | ||
Rat | SELP-4969R-B | Recombinant Rat SELP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | SELP-4969R | Recombinant Rat SELP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rabbit | SELP-1223R | Recombinant Rabbit SELP Protein, His-tagged | E.coli | N-His | Val39-Glu195 | |
Bos taurus (Bovine) | RFL32002BF | Recombinant Full Length Bovine P-Selectin(Selp) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (42-646) | |
Cynomolgus Monkey | SELP-192C | Recombinant Cynomolgus SELP, His-tagged | Human Cell | His | Met1-Ala771 | |
Cynomolgus Monkey | SELP-001CCL | Recombinant Cynomolgus SELP cell lysate | Human Cell | N/A | ||
Mus musculus (Mouse) | RFL7276MF | Recombinant Full Length Mouse P-Selectin(Selp) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (42-768) | |
Ovis aries (Sheep) | RFL20752OF | Recombinant Full Length Sheep P-Selectin(Selp) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (33-769) | |
Rattus norvegicus (Rat) | RFL29916RF | Recombinant Full Length Rat P-Selectin(Selp) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (42-768) | |
Rhesus | SELP-530R | Recombinant Rhesus SELP Protein, Fc-tagged | HEK293 | Fc | Met1-Ala771 | |
Rhesus | SELP-531R | Recombinant Rhesus SELP protein, His-tagged | HEK293 | His | Met1-Ala771 | |
Zebrafish | SELP-8050Z | Recombinant Zebrafish SELP | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- SELP Related Research Area
SELP involved in several pathways and played different roles in them. We selected most pathways SELP participated on our site, such as Cell adhesion molecules (CAMs), Malaria, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SELP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cell adhesion molecules (CAMs) | CLDNA;CLDN5B;NRXN1;CLDNC;NFASCA;ITGAM;NCAM2;ITGB1A;CD6 |
Malaria | KLRC4-KLRK1;CD81;THBS4;IL12A;HBA-A2;IL1B;SDC2;GYPB;KLRB1 |
Staphylococcus aureus infection | C5AR1;FCGR4;HLA-DQB1;MBL2;PLG;HLA-DRA;SELPLG;DSG1C;C3 |
SELP has several biochemical functions, for example, calcium-dependent protein binding, fucose binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SELP itself. We selected most functions SELP had, and list some proteins which have the same functions with SELP. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
calcium-dependent protein binding | S100PBP;A2M;S100P;MYO1D;TSG101;S100A6;C9orf9;KCNIP3;MBL2 |
fucose binding | FUOM;FUCA1;FUCA2;SELP |
glycoprotein binding | Serpina1c;DNAJA2;CALR;HSPA5;FOXRED2;B2M;CNTN1;FYN;LRRK2 |
glycosphingolipid binding | LAMA1;SELP;SELL;Il2;LYN;LAMB1;LAMC1;Cel |
heparin binding | ADAMTS3;ECM2;PCOLCE2;ABP1;APOA5;CCL15;HDGF;PGF;Itgam&Itgb2 |
lipopolysaccharide binding | TREM2;HMGB1;SCARB1;CD6;TLR2;TLR4;RNASE7;BPIFC;SPON2 |
oligosaccharide binding | CHID1;SELP;DCBLD1;RS1A;SELE;LOXL2 |
protein binding | SH3PXD2B;CCDC88A;UGGT2;CCDC6;CCT6A;IL11;HTN1;TMEM31;SCMH1 |
sialic acid binding | ST8SIA2;AGRN;ST8SIA3;SELP;FCN1;ADIPOQ;L1CAM;SELE;Siglece |
SELP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SELP here. Most of them are supplied by our site. Hope this information will be useful for your research of SELP.
SELPLG
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All SELP Products
Required fields are marked with *
My Review for All SELP Products
Required fields are marked with *