SIRPA

  • Official Full Name

    signal-regulatory protein alpha

  • Overview

    plays a role in macrophage fusion
  • Synonyms

    SIRPA; signal-regulatory protein alpha; tyrosine-protein phosphatase non-receptor type substrate 1; mSIRP-alpha1; sirp-alpha-1; myD-1 antigen; SHP substrate 1; inhibitory receptor SHPS-1; signal-regulatory protein alpha-1; CD172 antigen-like family member A; brain immunological-like with tyrosine-based motifs; protein tyrosine phosphatase, non-receptor type substrate 1; brain Ig-like molecule with tyrosine-based activation motifs; Bit; P84; SIRP; SHP-1; CD172a; Ptpns1; SHPS-1; AI835480;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Bovine
  • Chicken
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • CHO
  • CHO cells
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • Human Cells
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mammalian Cells
  • C
  • Fc
  • hFc
  • Avi
  • His
  • mFc
  • DYKDDDDK
  • His(C
  • ter)
  • GST
  • Myc
  • His (Fc)
  • His\Avi
  • His|Avi
  • His|T7
  • SUMO
  • human|IgG1|Fc
  • IgG1 Fc
  • lFc
  • MIgG2a Fc
  • Mouse|IgG1|Fc
  • DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SIRPA-202H Active Recombinant Human SIRPA protein, Fc-tagged CHO Fc
Human SIRPA-170H Active Recombinant Human SIRPA Protein, Fc-tagged, Biotinylated CHO Fc (Gly27-Arg370) & (Glu31-Arg370)
Human SIRPA-806H Active Recombinant Human SIRPA Protein, Fc Chimera CHO Fc
Human SIRPA-052H Active Recombinant Human SIRPA protein, His/Avi-tagged, Biotinylated CHO cells His/Avi Glu31-Asn371
Human SIRPA-2155H Active Recombinant Human SIRPA protein, His-tagged HEK293 His Glu 31 - Arg 369
Human SIRPA-0685H Active Recombinant Human SIRPA protein, lFc-tagged HEK293 lFc Glu31-Ser148
Human SIRPA-0684H Active Recombinant Human SIRPA protein, lFc-tagged HEK293 lFc Glu31-Arg369
Human SIRPA-1170H Recombinant Human SIRPA protein(Met1-Arg370), His-Avi-tagged, Biotinylated HEK293 C-His-Avi Met1-Arg370
Human SIRPA-0698H Active Recombinant Human SIRPA protein, lFc-tagged HEK293 lFc Glu31-Ser149
Human SIRPA-1239H Acitve Recombinant Human SIRPA protein(Met1-Arg369), His-tagged HEK293 C-His Met1-Arg369
Human SIRPA-051H Active Recombinant Human SIRPA protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi Glu31-Asn371
Human SIRPA-1389H Acitve Recombinant Human SIRPA protein(Met1-Arg369(S44L, S50T, I52T, H54R, V57A)), mFc-tagged HEK293 C-mFc Met1-Arg369(S44L, S50T, I52T, H54R, V57A)
Human SIRPA-0699H Active Recombinant Human SIRPA protein, lFc-tagged HEK293 lFc Glu31-Arg370
Human SIRPA-2388H Recombinant Human SIRPA protein(Met1-Arg370), hFc&Avi-tagged, Biotinylated HEK293 C-hFc&Avi Met1-Arg370
Human SIRPA-1388H Acitve Recombinant Human SIRPA protein(Met1-Arg369), mFc-tagged HEK293 C-mFc Met1-Arg369
Human SIRPA-3306H Active Recombinant Human SIRPA protein(Met1-Arg369(S44L, S50T, I52T, H54R, V57A)), His-tagged HEK293 C-His Met1-Arg369(S44L, S50T, I52T, H54R, V57A)
Human SIRPA-808H Active Recombinant Human SIRPA protein, mFc-tagged HEK293 mFc Glu 31 - Arg 370
Human SIRPA-3218H Active Recombinant Human SIRPA protein, His-tagged HEK293 His Met1-Arg370,Gly75Ala
Human SIRPA-807H Recombinant Human SIRPA protein, Fc-tagged (HPLC-verified) HEK293 Mouse/IgG1/Fc 340
Human SIPRA-4843H Recombinant Human SIRPA protein, His-tagged HEK293 His Glu31-Arg370
Human SIRPA-2678H Recombinant Human SIRPA, His-tagged E.coli His C-term-351aa
Human SIRPA-2298HCL Recombinant Human SIRPA cell lysate Human Cell N/A
Human SIRPA-4554H Recombinant Human SIRPA protein, His&Myc-tagged E.coli His&Myc 1-131aa
Human SIRPA-195H Recombinant Human SIRPA Protein, His\Avi-tagged Human Cell His\Avi
Human SIRPA-346H Recombinant Human SIRPA protein, mouse IgG1 Fc-tagged (HPLC-verified) HEK293 Mouse/IgG1/Fc 340
Human SIRPA-019H Recombinant Human SIRPA Protein, C-His-tagged E.coli C-His
Human SIRPA-3493H Recombinant Human SIRPA protein, His-SUMO-tagged E.coli His-SUMO 31-373aa
Human SIRPA-0686H Active Recombinant Human SIRPA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu31-Arg369
Human SIRPA-2610H Recombinant Human SIRPA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SIRPA-721H Recombinant Human SIRPA Protein HEK293 504
Human SIRPA-5063H Recombinant Human SIRPA protein, hFc-Myc-tagged HEK293 hFc-Myc 31-370aa
Human SIRPA-0702H Active Recombinant Human SIRPA protein, mFc-Avi-tagged, Biotinylated HEK293 mFc-Avi Glu31-Arg370
Human SIRPA-293H Recombinant Human SIRPA Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Glu31-Arg370
Human SIRPA-722H Recombinant Human SIRPA Protein, Fc-tagged HEK293 Fc 504
Human SIRPA-3218HAF555 Recombinant Human SIRPA Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 351
Human SIRPA-4023H Recombinant Human SIRPA Protein (Met1-Arg370), C-His tagged Mammalian cells C-His Met1-Arg370
Human SIRPA-724H Recombinant Human SIRPA Protein, IgG1 Fc-tagged HEK293 IgG1 Fc 504
Human SIRPA-5657H Recombinant Human SIRPA Protein E.coli Tag Free
Human SIRPA-0764H Recombinant Human SIRPA Protein (Glu31-Arg370), N-His tagged E.coli N-His Glu31-Arg370
Human SIRPA-1372H Recombinant Human SIRPA protein(Met1-Arg369), His-tagged, Biotinylated HEK293 C-His Met1-Arg369
Human SIRPA-2690H Active Recombinant Human SIRPA protein, hFc&His-tagged HEK293 hFc&His Glu31-Arg370
Human SIRPA-5658H Recombinant Human SIRPA Protein (Glu31-Arg370), C-Fc tagged Mammalian cells C-Fc Glu31-Arg370
Human SIRPA-4672H Active Recombinant Human SIRPA Protein, Fc-tagged, PE-Labeled HEK293 Fc Glu 31 - Arg 370
Human SIRPA-13H Active Recombinant Human SIRPA Protein, His-tagged HEK293 His 27-373
Human SIRPA-1276H Active Recombinant Human SIRPA protein, His-tagged HEK293 His Glu31-Arg370
Human SIRPA-5659H Recombinant Human SIRPA Protein (Lys32-Asn372), C-His tagged Mammalian cells C-His Lys32-Asn372
Human SIRPA-324H Recombinant Human SIRPA protein, His-Avi-tagged HEK293 His-Avi Glu31-Arg369
Human SIRPA-3218HAF488 Recombinant Human SIRPA Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 351
Human SIRPA-0726H Active Recombinant Human SIRPA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu31-Arg369
Human SIRPA-226H Recombinant Human SIRPA Protein, V5, Glu31-Arg370, S42F, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu31-Arg370, S42F
Human SIRPA-475HG Active GMP Recombinant Human SIRPA protein HEK293 DNA sequence encoding Human SIRP alpha(NCBI Reference Sequence: NP_542970.1) was expressed with His tag at the C-terminal.
Human SIRPA-347H Active Recombinant Human SIRPA Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi Glu 31 - Arg 370
Human SIRPA-224H Recombinant Human SIRPA Protein, V3, Glu31-Arg369, H54L, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu31-Arg369, H54L
Human SIRPA-227H Recombinant Human SIRPA Protein, V6, Glu31-Arg370, S105P, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu31-Arg370, S105P
Human SIRPA-3218HAF647 Recombinant Human SIRPA Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 351
Human SIRPA-324HB Recombinant Human SIRPA protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Glu31-Arg370
Human SIRPA-3218HF Recombinant Human SIRPA Protein, His-tagged, FITC conjugated HEK293 His 351
Human SIRPA-228H Recombinant Human SIRPA Protein, V8, Glu31-Arg369, S44L, S50T, I52T, H54R, V57A, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu31-Arg369, S44L, S50T, I52T, H54R, V57A
Human SIRPA-3222H Recombinant Human SIRPA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SIRPA-515H Recombinant Human SIRPA Protein (Met1-Arg370), MIgG2a Fc-tagged HEK293 MIgG2a Fc Met1-Arg370
Human SIRPA-225H Recombinant Human SIRPA Protein, V4, Glu31-Arg370, E33G, L44S, T50S, T52I, R54H, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu31-Arg370, E33G, L44S, T50S, T52I, R54H
Human SIRPA-4843H Recombinant Human SIRPA protein, His-tagged (HPLC-verified) HEK293 His Glu31-Arg370
Human SIRPA-723H Recombinant Human SIRPA Protein, Fc-tagged CHO Fc 504
Human SIRPA-520H Recombinant Human SIRPA Protein, Fc-tagged HEK293 Fc Glu31-Arg370
Human SIRPA-5488H Recombinant Human SIRPA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SIRPA-3218HB Recombinant Human SIRPA protein, His-tagged, Biotinylated HEK293 His
Human SIRPA-933H Recombinant Human SIRPA Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human SIRPA-932H Recombinant Human SIRPA Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human SIRPA-1847H Recombinant Human SIRPA protein, GST-tagged E.coli GST 158-508 aa
Mouse SIRPA-1251M Acitve Recombinant Mouse SIRPA protein(Met1-Asn373), His-tagged HEK293 C-His Met1-Asn373
Mouse SIRPA-936M Recombinant Mouse SIRPA protein, Fc-tagged HEK293 human/IgG1/Fc Lys32-Asn373
Mouse Sirpa-5667M Recombinant Mouse Sirpa protein, His & T7-tagged E.coli His/T7 Thr56~Arg296 (Accession # P97797)
Mouse SIRPA-937M Active Recombinant Mouse SIRPA protein, His-tagged HEK293 His Lys 32 - Asn 373
Mouse SIRPA-1650MCL Recombinant Mouse SIRPA cell lysate Human Cell N/A
Mouse Sirpa-5882M Recombinant Mouse Sirpa Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SIRPA-348M Active Recombinant Mouse SIRPA protein, mFc-tagged HEK293 mFc Lys 32 - Asn 373
Mouse SIRPA-936MAF488 Recombinant Mouse Sirpa Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Lys32-Asn373
Mouse SIRPA-936MAF555 Recombinant Mouse Sirpa Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Lys32-Asn373
Mouse SIRPA-937MAF488 Recombinant Mouse SIRPA Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Lys32-Asn373
Mouse SIRPA-0701M Active Recombinant Mouse SIRPA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Lys32-Asn373
Mouse SIRPA-937MAF555 Recombinant Mouse SIRPA Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Lys32-Asn373
Mouse SIRPA-683M Active Recombinant Mouse SIRPA protein, Fc-tagged HEK293 Fc Lys 32 - Asn 373
Mouse Sirpa-5734M Recombinant Mouse Sirpa Protein (Lys32-Asn372), C-Fc tagged Mammalian cells C-Fc Lys32-Asn372
Mouse Sirpa-6805M Recombinant Mouse Sirpa Protein (Lys32-Leu146), Fc tagged Mammalian cells Fc Lys32-Leu146
Mouse SIRPA-2177M Active Recombinant Mouse SIRPA protein, hFc-tagged HEK293 hFc Met1-Asn373
Mouse SIRPA-4671M Active Recombinant Mouse SIRPA Protein, His-tagged, PE-Labeled HEK293 His Lys 32 - Asn 373
Mouse SIRPA-936MF Recombinant Mouse Sirpa Protein, hFc-tagged, FITC conjugated HEK293 hFc Lys32-Asn373
Mouse SIRPA-937MF Recombinant Mouse SIRPA Protein, His-tagged, FITC conjugated HEK293 His Lys32-Asn373
Mouse SIRPA-936MAF647 Recombinant Mouse Sirpa Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Lys32-Asn373
Mouse SIRPA-937MAF647 Recombinant Mouse SIRPA Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Lys32-Asn373
Rat Sirpa-5668R Recombinant Rat Sirpa protein, His & T7-tagged E.coli His/T7 Asp116~Asp308 (Accession # P97710)
Rat SIRPA-5407R Recombinant Rat SIRPA Protein Mammalian Cell His
Rat Sirpa-23R Active Recombinant Rat Sirpa protein, His-tagged HEK293 His Met1-Asn373
Rat Sirpa-195R Recombinant Rat Sirpa protein, His-tagged Insect Cell His
Rat SIRPA-1005RCL Recombinant Rat SIRPA cell lysate Human Cell N/A
Rat SIRPA-0697R Active Recombinant Rat SIRPA protein, Fc-tagged HEK293 Fc Lys32-Asn373
Rat Sirpa-23RAF488 Recombinant Rat Sirpa Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 353
Rat SIRPA-5066R Recombinant Rat SIRPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Sirpa-23RAF647 Recombinant Rat Sirpa Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 353
Rat SIRPA-5066R-B Recombinant Rat SIRPA Protein Pre-coupled Magnetic Beads HEK293
Rat Sirpa-23RF Recombinant Rat Sirpa Protein, His-tagged, FITC conjugated HEK293 His 353
Rat Sirpa-23RAF555 Recombinant Rat Sirpa Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 353
Bos taurus (Bovine) RFL19180BF Recombinant Full Length Bovine Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1(Sirpa) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-506)
Bovine SIRPA-2B-B Recombinant Bovine SIRPA Protein Pre-coupled Magnetic Beads HEK293
Bovine SIPRA-133B Recombinant Bovine SIRPA Protein, Fc-tagged Mammalian Cells Fc Asp31 - Asn368
Bovine SIPRA-132B Recombinant Bovine SIRPA Protein, His-tagged Mammalian Cells His Asp31 - Asn368
Bovine SIRPA-2B Recombinant Bovine SIRPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus SIRPA-343C Active Recombinant Cynomolgus SIRPA protein, His-tagged HEK293 His Glu 31 - Asn 370
Cynomolgus SIRPA-0700C Active Recombinant Cynomolgus SIRPA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu31-Asn370
Cynomolgus SIRPA-0703C Active Recombinant Cynomolgus SIRPA protein, Fc-tagged HEK293 Fc Glu31-Asn370
Cynomolgus SIRPA-3654C Active Recombinant Cynomolgus SIRPA protein, His-tagged HEK293 His Met1-Tyr372
Cynomolgus SIRPA-1158C Recombinant Cynomolgus SIRPA protein(Met1-Tyr372), His-tagged HEK293 C-His Met1-Tyr372
Cynomolgus SIRPA-342C Recombinant Cynomolgus SIRPA protein, Fc-tagged HEK293 human/IgG1/Fc 340
Homo sapiens (Human) RFL10554HF Recombinant Full Length Human Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1(Sirpa) Protein, His-Tagged E.coli expression system His Full Length (31-504)
Mus musculus (Mouse) RFL15669MF Recombinant Full Length Mouse Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1(Sirpa) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (32-513)
Rattus norvegicus (Rat) RFL478RF Recombinant Full Length Rat Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1(Sirpa) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (32-509)
Chicken SIRPA-3300C Recombinant Chicken SIRPA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

SIRPA involved in several pathways and played different roles in them. We selected most pathways SIRPA participated on our site, such as BDNF signaling pathway, Cardiac Progenitor Differentiation, Cell surface interactions at the vascular wall, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIRPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
BDNF signaling pathwayCDKL5;SIRPA;SYN1;YBX1;CFL1;EIF4E;EIF2S1;EGR2;GRIP1
Cardiac Progenitor DifferentiationTBX5;LIN28A;NIPAL1;TBX20;ZFP42;T;NKX2;SOX1;LIN28B
Cell surface interactions at the vascular wallFN1B;SLC16A8;ANGPT2A;JAM2B;AMICA1;SLC7A8A;GRB7;GRB14;PPIA
Cell-Cell communicationF11R.2;PLECA;CLDN16;CDH11;CDH13;CDH10A;CDH9;CTNND1;INADL
HemostasisDOK2;DOCK2;CABLES2;ANXA2A;SLC8A2A;NADL1.1;HBB-BH1;DOCK9;PROCA
IL-1 Signaling PathwaySIRPA;IKBKAP;IL1RN
Osteoclast differentiationMAPK13;LILRA1;CSF1R;LILRA4;ITGB3;MAPK10;PPP3CB;IL1R1;PIK3CD
Prolactin Signaling PathwayFOS;STAT1;SRC;CSH;TNFRSF11A;NRAS;GALT;GSK3B;MAPK11

SIRPA has several biochemical functions, for example, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIRPA itself. We selected most functions SIRPA had, and list some proteins which have the same functions with SIRPA. You can find most of the proteins on our site.

Function Related Protein
SH3 domain bindingSKAP1;CIT;CCDC6;ZFP106;ADAM15;CYBA;LANCL1;ELMO1;USP8

SIRPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIRPA here. Most of them are supplied by our site. Hope this information will be useful for your research of SIRPA.

NOL3; PTPN6; TRIM2; HTT; GRB2

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
09/30/2020

    I am thankful for the immense support provided by this protein reagent for my experimental work! 

    06/14/2020

      This protein substance is truly an indispensable tool in my laboratory!

      09/03/2019

        Its performance is stable and reliable, and the manufacturer's quality control ensures that every experiment runs smoothly.

        Q&As (0)

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