| Species : |
Human |
| Source : |
Yeast |
| Tag : |
Non |
| Description : |
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
| Form : |
White or off-white lyophilized powder |
| Bio-activity : |
1.2×10^6U~2.0×10^6 U/mg pro. According to the method specified in the Chinese Pharmacopoeia 2020 edition, the biological activity is determined by assessing the stimulatory effect of EGF on mouse fibroblast cell line BALB/3T3. |
| Molecular Mass : |
6.2 ± 0.6 kDa |
| Endotoxin : |
< 1 EU/μg |
| Purity : |
≥98%(SDS-PAGE); ≥98%(HPLC) |
| Applications : |
1. Cell Culture: Preparation of Serum-Free Medium; Cell Culture; Promotion of Cell Proliferation, Growth, and Differentiation
2. As a medication (gel, eye drops, etc.): Treatment of burn and scald wounds; Treatment of chronic ulcer wounds; Treatment of various fresh and difficult-to-heal skin wounds
3. As a Medication (e.g., gel, eye drops, etc.): Repair; Wrinkle reduction and anti-aging; Spot removal, etc. |
| Storage : |
Store at -15 to -20 centigrade, stable for up to 24 months. |
| Solubility : |
Soluble in water or buffer solution. |
