"IL18BP" Related Products

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Recombinant Human Interleukin 18 Binding Protein

Cat. No.: IL18BP-1656H
Description: IL-18-binding protein (IL-18BP) is a secreted glycoprotein that functions as a natural anti-inflammatory and immunosuppressive molecule neutralizing the effects of high IL18 levels during inflammation. There are four variants of IL-18BP and IL18BPa is the predominant form showing the highest affinity towards IL18. that IL-18 BPa:Fc has the potential to amplify anti-inflammatory actions of immunosuppressive drugs, and thus may prove to be a valuable novel pharmacological component in the treatment of human autoimmune diseases.
Molecular Weight: The predicted molecular weight of Recombinant Human IL-18 BPa is Mr 44.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-75 kDa.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >95% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: IL18BP interleukin 18 binding protein [Homo sapiens ]
Synonyms: IL18BP; interleukin 18 binding protein; tadekinig-alfa; IL18BPa; OTTHUMP00000179143; MC51L-53L-54L homolog gene product; IL-18BP; OTTHUMP00000179141; Tadekinig-alfa;Interleukin-18-binding protein
Gene ID: 10068
mRNA Refseq: NM_001039659
Protein Refseq: NP_001034748
MIM: 604113
UniProt ID: O95998
Chromosome Location: 11q13
Function: interleukin-18 binding; receptor antagonist activity

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