"TNFRSF17" Related Products

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Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 17

Cat. No.: TNFRSF17-5253H
Product Overview: RecombinantTNFRSF17 is a disulfide-linked monomer protein consisting of 54 amino acidresidue subunits, and migrates as an approximately 6kDa protein undernon-reducing and reducing conditions in SDS-PAGE. The protein encodedby this gene is a member of the TNF-receptor superfamily, and was lyophilized from a 0.2 μm filtered 30% acetonitrile, 0.1%TFA solution pH 7.5.
Description: TNFRSF17 (B cell maturation) is a nonglycosylated integral membrane typeI protein that is preferentially expressed in mature B lymphocytes.TheN-terminal part of both mouse and human proteins contains a conserved six-cysteine motif.
Source: Human
Host: E. coli
Purity: >95%, asdetermined by SDS-PAGE and HPLC.
Sequence: MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNAILWTCL
Molecular Weight: 6kDa
Biological Activity: TheED(50) was not determined.
Endotoxin: Endotoxincontent was assayed using a LAL gel clot method. Endotoxin level was found tobe less than 0.1 ng/µg(1EU/µg).
Reconstitution: A quickspin of the vial followed by reconstitution in distilled water to aconcentration not less than 0.1 mg/mL. This solution can then be diluted intoother buffers.
Storage: Thelyophilized protein is stable for at least 2 years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquotsat 2°C - 8°C for one month, or at -20°C for six months, with a carrierprotein without detectable loss of activity. Avoid repeated freeze/thawcycles.
OfficialSymbol: TNFRSF17
Pathways: Cytokine-cytokinereceptor interaction; Intestinal immune network for IgA production
Gene Name: TNFRSF17 tumor necrosis factor receptor superfamily,member 17 [ Homo sapiens ]
Synonyms: TNFRSF17;tumor necrosis factor receptor superfamily, member 17; BCM;BCMA; CD269; tumor necrosis factor receptor superfamily member 17; OTTHUMP00000160261;B-cell maturation factor; B cell maturation antigen; B-cell maturationprotein
Gene ID: 608
mRNA Refseq: NM_001192
Protein Refseq: NP_001183
MIM: 109545
UniProt ID: Q02223
Chromosome Location: 16p13
Function: receptor activity;tumor necrosis factor receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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