Cat. No. : |
TNFRSF17-5253H |
Product Overview : |
RecombinantTNFRSF17 is a disulfide-linked monomer protein consisting of 54 amino acidresidue subunits, and migrates as an approximately 6kDa protein undernon-reducing and reducing conditions in SDS-PAGE. The protein encodedby this gene is a member of the TNF-receptor superfamily, and was lyophilized from a 0.2 μm filtered 30% acetonitrile, 0.1%TFA solution pH 7.5. |
Description : |
TNFRSF17 (B cell maturation) is a nonglycosylated integral membrane typeI protein that is preferentially expressed in mature B lymphocytes.TheN-terminal part of both mouse and human proteins contains a conserved six-cysteine motif. |
Source : |
Human |
Host : |
E. coli |
Purity : |
>95%, asdetermined by SDS-PAGE and HPLC. |
Sequence : |
MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNAILWTCL |
Molecular Weight : |
6kDa |
Biological Activity : |
TheED(50) was not determined. |
Endotoxin : |
Endotoxincontent was assayed using a LAL gel clot method. Endotoxin level was found tobe less than 0.1 ng/µg(1EU/µg). |
Reconstitution : |
A quickspin of the vial followed by reconstitution in distilled water to aconcentration not less than 0.1 mg/mL. This solution can then be diluted intoother buffers. |
Storage : |
Thelyophilized protein is stable for at least 2 years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquotsat 2°C - 8°C for one month, or at -20°C for six months, with a carrierprotein without detectable loss of activity. Avoid repeated freeze/thawcycles. |
OfficialSymbol : |
TNFRSF17 |
Pathways : |
Cytokine-cytokinereceptor interaction; Intestinal immune network for IgA production |