Mouse Anti-TREM1 Monoclonal Antibody
Cat.No. : | DMABT-H18611 |
Product Overview : | Mouse Anti-TREM1 Monoclonal Antibody |
- Specification
- Gene Information
- Related Products
Antigen Description : | TREM-1 is a 30 kD glycoprotein also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. It is a Type I membrane protein that contains an immunoglobulin-like V-type domain. Alternatively spliced protein variant may be secreted. TREM-1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM-1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM-1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM-1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock. |
Target : | TREM1 |
Immunogen : | Recombinant human TREM-1 |
Host : | Mouse |
Isotype : | IgG2b, kappa |
species : | Human |
Conjugation : | N/A |
Applications : | ELISA,WB,Flow Cyt |
Preparation : | The antibody was purified by affinity chromatography. |
Usage recommendation : | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.5 μg per million cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Concentration : | 0.5 mg/ml |
Storage : | The antibody solution should be stored undiluted at 4 °C. |
Size : | 25 μg;100 μg |
Gene Name : | TREM1 triggering receptor expressed on myeloid cells2[ Homo sapiens ] |
Official Symbol : | TREM1 |
Synonyms : | TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; TREM-1; |
Gene ID : | 54210 |
mRNA Refseq : | NM_001242589 |
Protein Refseq : | NP_001229518 |
MIM : | 605085 |
UniProt ID : | Q9NP99 |
Chromosome Location : | 6p21.1 |
Pathway : | Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | receptor activity; |
Products Types
◆ Recombinant Protein | ||
TREM1-116H | Recombinant Human TREM1 Protein, C-His-tagged | +Inquiry |
TREM1-3842H | Recombinant Human TREM1 protein(Met1-Arg200), His-tagged | +Inquiry |
TREM1-485H | Recombinant Human TREM1 Protein, His-tagged | +Inquiry |
TREM1-886H | Recombinant Human TREM1 protein(Met1-Arg200), His&hFc-tagged | +Inquiry |
TREM1-212H | Recombinant Human TREM1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TREM1-2140HCL | Recombinant Human TREM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket