"IL28A" Related Products

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Recombinant Human Interleukin 28A

Cat. No.: IL28A-539H
Product Overview: Recombinant human IL28A was expressed in E. coli and purified by using conventional chromatography techniques.
Description: IFN-lambda-1, -2, and -3 (also known as IL29, IL28A and IL28B respectively) are distantly related to the IL10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.
Source: Human
Host: E.coli
Form: Supplied as a lyophilized powder.
Purity: >98% pure by SDS PAGE and HPLC
Sequence: Region of IFN Gamma 2 protein corresponding to amino acids PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV.
Molecular Mass: 19.6 kDa
Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity: Determined by its ability to activate STAT following receptor-ligand interaction.
Storage: Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
Official Symbol: IL28A
Synonyms: IL28A; interleukin 28A (interferon, lambda 2);IFNL2; IL-28A; IFN-lambda-2; interferon lambda 2; interferon-lambda 2; Interleukin-28A; Interferon lambda-2; IFN-lambda-2; ZCYTO20; Cytokine ZCYTO20
Gene ID: 282616
mRNA Refseq: NM_172138
Protein Refseq: NP_742150
MIM: 607401
UniProt ID: Q8IZJ0
Chromosome Location: 19q13.13
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: Cytokine activity

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