| Cat. No. : |
IL28A-539H |
| Description : |
IFN-lambda-1, -2, and -3 (also known as IL29, IL28A and IL28B respectively) are distantly related to the IL10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. |
| Source : |
Human |
| Host : |
E.coli |
| Form : |
Supplied as a lyophilized powder. |
| Purity : |
>98% pure by SDS PAGE and HPLC |
| Sequence : |
Region of IFN Gamma 2 protein corresponding to amino acids PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV. |
| Molecular Mass : |
19.6 kDa |
| Applications : |
Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
| Endotoxin Levels : |
Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
| Bioactivity : |
Determined by its ability to activate STAT following receptor-ligand interaction. |
| Storage : |
Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
