Native Human Beta 2 MicroGlobulin

Cat.No.: B2M-8046H
Product Overview: Human Beta 2 MicroGlobulin was purified from Human Urine.
Description: Serum beta-2 Microglobulin is an endogenous marker for renal function an has been shown to be an independent predictor of mortality in older adults. It has been reported that Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders.
Source: Human Urine
Species: Human
Form: Phosphate Buffered Saline
Molecular Mass: 11.8 kDa
Purity: >98% by SDS-PAGE
Storage: 2-8 °C
Concentration: Typically >2.0 mg/mL
Gene Name: B2M beta-2-microglobulin [ Homo sapiens ]
Official Symbol: B2M
Synonyms: B2M; beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules;
Gene ID: 567
mRNA Refseq: NM_004048
Protein Refseq: NP_004039
MIM: 109700
UniProt ID: P61769
Chromosome Location: 15q21-q22.2
Pathway: Adaptive Immune System, organism-specific biosystem; Amyloids, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and
Function: protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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