Recombinant Human ARG1, His-tagged

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Recombinant Human ARG1, His-tagged

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Cat.No. : ARG1-9810H
Product Overview : Recombinant Human ARG1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-236a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : ARG1 arginase, liver [ Homo sapiens ]
Official Symbol : ARG1
Synonyms : ARG1; arginase, liver; arginase-1; type I arginase; liver-type arginase;
Gene ID : 383
mRNA Refseq : NM_000045
Protein Refseq : NP_000036
MIM : 608313
UniProt ID : P05089
Chromosome Location : 6q23
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; IL4-mediated signaling events, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;
Function : arginase activity; hydrolase activity; manganese ion binding; metal ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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