Recombinant Human CUL1, GST-tagged
Cat.No. : | CUL1-11701H |
Product Overview : | Recombinant Human CUL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-352a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CUL1 cullin 1 [ Homo sapiens ] |
Official Symbol : | CUL1 |
Synonyms : | CUL1; cullin 1; cullin-1; CUL-1; MGC149834; MGC149835; |
Gene ID : | 8454 |
mRNA Refseq : | NM_003592 |
Protein Refseq : | NP_003583 |
MIM : | 603134 |
UniProt ID : | Q13616 |
Chromosome Location : | 7q36.1 |
Pathway : | APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; |
Function : | protein binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
CUL1-688H | Recombinant Human CUL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CUL1-648H | Recombinant Human CUL1 Protein, His-tagged | +Inquiry |
Cul1-2374M | Recombinant Mouse Cul1 Protein, Myc/DDK-tagged | +Inquiry |
CUL1-2080M | Recombinant Mouse CUL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CUL1-2239H | Recombinant Human CUL1 Protein (Met1-Glu250), His tagged | +Inquiry |
◆ Lysates | ||
CUL1-7185HCL | Recombinant Human CUL1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionTechniques such as immunohistochemistry, Western blotting, and gene expression analysis are commonly used to study CUL1 protein expression and function in clinical research.
Yes, CUL1 protein has been implicated in various diseases, including neurodegenerative disorders and cardiovascular diseases, due to its role in protein degradation and cellular regulation.
While CUL1 protein levels are altered in certain cancers, it is not commonly used as a standalone biomarker. However, it may be part of a panel of markers used for cancer diagnosis.
Yes, mutations in the CUL1 gene have been linked to a rare genetic disorder called Cullin-Ring Ligase 1 Syndrome, which is characterized by developmental delays and intellectual disabilities.
Dysregulation of CUL1 protein can lead to the abnormal degradation of cell cycle regulators, resulting in uncontrolled cell division and potentially contributing to tumorigenesis.
Customer Reviews (3)
Write a reviewI highly recommend the CUL1 protein for a variety of research applications.
It demonstrates excellent performance in ELISA, consistently delivering accurate and reliable results.
the CUL1 protein has proven to be an invaluable tool in protein electron microscopy structure analysis.
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