||Recombinant Human PDE5A, fused with at the C-terminus to a His-tag, was expressed in Sf9 insect cells.
||This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
||Sf9 insect cells
||Liquid. In 50mM triethanolamine, pH 7.4, containing 1mM DTT, 100mM NaCl, 20% glycerol.
||Avoid freeze/thaw cycles.