"IL21" Related Products

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Recombinant Human IL21, His-tagged

Cat.No.: IL21-15H
Product Overview: Recombinant Human Interleukin-21/IL-21 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln23-Ser155) of Human IL-21 fused with a polyhistidine tag at the C-terminus.
Description: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source: Human cells
Species: Human
Tag: His
AA Sequence: QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNER IINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGS EDSVDHHHHHH
Endotoxin: Less than 0.1 ng/µg (1 IEU/µg).
Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Gene Name: IL21 interleukin 21 [ Homo sapiens (human) ]
Official Symbol: IL21
Synonyms: IL21; interleukin 21; Za11; IL-21; CVID11; interleukin-21; interleukin-21 isoform
Gene ID: 59067
mRNA Refseq: NM_021803
Protein Refseq: NP_068575
MIM: 605384
UniProt ID: Q9HBE4
Chromosome Location: 4q26-q27
Pathway: Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Jak-STAT signaling pathway
Function: cytokine activity; cytokine receptor binding; interleukin-2 receptor binding

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